Étiquette : épidémiologie

Conducting Qualitative Research With Psychedelic Psychopharmacologists : Challenges of Co-Production in an Era of Interdisciplinarity, Tehseen Noorani, 2017

Conducting Qualitative Research With Psychedelic Psychopharmacologists : Challenges of Co-Production in an Era of Interdisciplinarity Tehseen Noorani SAGE Research Methods Cases Part 2,  March 3, 2017, 1-14 Doi : 10.4135/9781526404862   Abstract From 2013 to 2015, I worked as a postdoctoral research fellow with a team of pharmacologists experimenting with psilocybin, an illegal psychoactive compound found in psychedelic mushrooms. The team had conducted an open-label clinical trial with long-term cigarette smokers, using psilocybin-assisted psychotherapy to help them quit. The smoking outcomes were very promising, occurring alongside many other profound positive life-changes. The team wanted to investigate further the mechanisms of change by which the study led [...]

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On the Relationship between Classic Psychedelics and Suicidality : A Systematic Review, Richard J. Zeifman et al., 2021

On the Relationship between Classic Psychedelics and Suicidality : A Systematic Review Richard J. Zeifman, Nikhita Singhal, Leah Breslow, & Cory R. Weissman ACS Pharmacology & Translational Science, 2021, 4, (2), 436-451 Doi : 10.1021/acsptsci.1c00024 Abstract Use of classic psychedelics (e.g., psilocybin, ayahuasca, lysergic acid diethylamide) is increasing and psychedelic therapy is receiving growing attention as a novel mental health intervention. Suicidality remains a potential safety concern associated with classic psychedelics and is, concurrently, a mental health concern that psychedelic therapy may show promise in targeting. Accordingly, further understanding of the relationship between classic psychedelics and suicidality is needed. Therefore, we conducted a systematic review [...]

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Psychedelic Therapy and Suicide: A Myth Busted ?, Megan Brooks, Medscape, 01/02/2022

Psychedelic Therapy and Suicide : A Myth Busted ? Megan Brooks Medscape Psychiatry, February 01, 2022 www.medscape.com/viewarticle/967669_print   A commonly held belief that classic psychedelic therapy can trigger suicidal thoughts, actions, or other types of self-harm is not supported by research, and, in fact, the opposite may be true. Results from a meta-analysis of individual patient data showed that psychedelic therapy was associated with large, acute, and sustained decreases in suicidality across a range of clinical patient populations. "This is the first analysis to synthesize suicidality outcome data from recent clinical trials with psychedelics. It gives us a better understanding of the effects of psychedelics on suicidality in the [...]

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Cannabinoids, Pain, and Opioid Use Reduction : The Importance of Distilling and Disseminating Existing Data, Kent E. Hutchison et al., 2019

Cannabinoids, Pain, and Opioid Use Reduction : The Importance of Distilling and Disseminating Existing Data Kent E. HUTCHISON, Sarah L. HAGERTY, Jeffrey GALINKIN, Angela D. BRYAN, L. Cinnamon BIDWELL Cannabis and Cannabinoid Research, 2019, 4, (3), 158-164. Doi : 10.1089/can.2018.0052   Abstract The high prevalence of chronic pain conditions combined with an over-reliance on opioid prescriptions has resulted in an opioid epidemic and a desperate need for solutions. There is some debate about whether cannabis might play a role in addressing chronic pain conditions as well as the opioid epidemic. Recent surveys suggest that a large number of people are using cannabis as a treatment for [...]

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Cannabis-related diagnosis in pregnancy and adverse maternal and infant outcomes, Gretchen Bandoli et al., 2021

Cannabis-related diagnosis in pregnancy and adverse maternal and infant outcomes Gretchen Bandoli, Laura Jelliffe-Pawlowski, Benjamin Schumacher, Rebecca J. Baer, Jennifer N. Felder, Jonathan D. Fuchs, Scott P. Oltman, Martina A. Steurer, Carla Marienfeld Drug and Alcohol Dependence, 2021, 225, 108757. doi : 10.1016/j.drugalcdep.2021.108757   Abstract Background: Cannabis use and cannabis use disorders are increasing in prevalence, including among pregnant women. The objective was to evaluate the association of a cannabis-related diagnosis (CRD) in pregnancy and adverse maternal and infant outcomes. Methods: We queried an administrative birth cohort of singleton deliveries in California between 2011-2017 linked to maternal and infant hospital discharge records. We [...]

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Cannabis : An Emerging Treatment for Common Symptoms in Older Adults, Kevin H. Yang et al., Medscape.com, 2021

Cannabis : An Emerging Treatment for Common Symptoms in Older Adults Kevin H. Yang, BS; Christopher N. Kaufmann, PhD, MHS; Reva Nafsu, LVN; Ella T. Lifset; Khai Nguyen, MD, MHS; Michelle Sexton, ND; Benjamin H. Han, MD, MPH; Arum Kim, MD; Alison A. Moore, MD, MPH Journal of American Geriatric Society, 2021, 69, (1), 91-97. https://www.medscape.com/viewarticle/945238   Abstract and Introduction Abstract Background/Objectives: Use of cannabis is increasing in a variety of populations in the United States; however, few investigations about how and for what reasons cannabis is used in older populations exist. Design: Anonymous survey. Setting: Geriatrics clinic. Participants: A total of 568 adults 65 years and older. Intervention: Not applicable. Measurements: [...]

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Use of Genetically Informed Methods to Clarify the Nature of the Association Between Cannabis Use and Risk for Schizophrenia, Nathan A. Gillespie, Kenneth S. Kendler, 2020

Use of Genetically Informed Methods to Clarify the Nature of the Association Between Cannabis Use and Risk for Schizophrenia Nathan A. Gillespie, Kenneth S. Kendler JAMA Psychiatry,  Published online November 4, 2020   Cohort studies and meta-analyses have documented a robust association between cannabis use, heavy use, and misuse with future risk of schizophrenia.1-3 Despite adjusting for covariates, including current psychotic symptoms, other psychopathology, and social integration,(1) the ability of these models to determine the degree to which cannabis causes schizophrenia is limited and dependent on their ability to capture all relevant confounders. When evaluating efforts to reduce cannabis use as a means of [...]

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Trajectories of Nicotine and Cannabis Vaping and Polyuse. From Adolescence to Young Adulthood, H. Isabella Lanza, 2020

Trajectories of Nicotine and Cannabis Vaping and Polyuse. From Adolescence to Young Adulthood H. Isabella Lanza, PhD; Jessica L. Barrington-Trimis, PhD; RobMcConnell, MD; Junhan Cho, PhD; Jessica L. Braymiller, PhD; Evan A. Krueger, PhD, MPH, MSW; Adam M. Leventhal, PhD JAMA Network Open, 2020, 3, (10), :e2019181. doi : 10.1001/jamanetworkopen.2020.19181   Abstract IMPORTANCE : Little is known about cannabis vaping trajectories across adolescence and young adulthood or the co-occurrence with nicotine vaping. OBJECTIVE : To evaluate nicotine vaping and cannabis vaping trajectories from late adolescence to young adulthood (18 years of age) and the extent of polysubstance vaping. DESIGN, SETTING, AND PARTICIPANTS : In this prospective cohort study, 5 surveys [...]

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Adolescent treatment admissions for marijuana following recreational legalization in Colorado and Washington Jeremy Mennis, Gerald J. Stahler, 2020

Adolescent treatment admissions for marijuana following recreational legalization in Colorado and Washington Jeremy Mennis, Gerald J. Stahler Drug and Alcohol Dependence, 2020, 210, 107960 Doi : 10.1016/j.drugalcdep.2020.107960   A B S T R A C T Introduction : There is concern that recreational marijuana legalization (RML) may lead to increased cannabis use disorder (CUD) among youth due to increased marijuana use. This study investigates whether adolescent substance use disorder treatment admissions for marijuana use increased in Colorado and Washington following RML. Methods : Annual data on 2008–2017 treatment admissions for marijuana use from the SAMHSA TEDS-A dataset for adolescents age 12–17 were used to model state treatment [...]

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Frequent Cannabis Use in Depression Tripled Over Past Decade, Batya Swift Yasgur, 2020

Frequent Cannabis Use in Depression Tripled Over Past Decade Batya Swift Yasgur, MA, LSW Medscape, August 19, 2020 Not only are individuals with depression at significantly higher risk for cannabis use compared with those without depression, this trend has increased dramatically over the last decade, new research shows. Investigators analyzed data from more than 16,000 US adults between the ages of 20 and 59 years and found that those with depression had almost twice the odds of any past-month cannabis use compared with those without depression. Odds rose from 1.5 in the 2005-2006 period to 2.3 in the 2015-2016 period. Moreover, the odds ratio (OR) [...]

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