Catégorie : Editoriaux

Peter Webster added a comment to the article : REBUS and the Anarchic Brain : Toward a Unified Model of the Brain Action of Psychedelicss, R. Carhart-Harris et al., 2019

Peter Webster added a comment to the article : REBUS and the Anarchic Brain : Toward a Unified Model of the Brain Action of Psychedelicss R. L. Carhart-Harris and K. J. Friston, Pharmacological Reviews, 2019,  71, 316–344 https://doi.org/10.1124/pr.118.017160 https://www.grecc.org/publications/ressources-documentaires/pharmacologie/rebus-and-the-anarchic-brain-toward-a-unified-model-of-the-brain-action-of-psychedelics-r-l-carhart-harris-and-k-j-friston-2019/ Prediction : ultimately you will find that the Salience Network has a far greater importance for understanding psychedelic experience than the DMN. See: Menon V. (2015) Salience Network. In: Arthur W. Toga, editor. Brain Mapping: An Encyclopedic Reference, vol. 2, p. 597. Academic Press: Elsevier. In Doors of Perception, Aldous Huxley writes, [I was seeing] a bunch of flowers shining with their own inner light and all but quivering under the [...]

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First, Marijuana. Are Magic Mushrooms Next? – Barbara Feder Ostrov – Medscape – May 21, 2018.

First, Marijuana. Are Magic Mushrooms Next ? Barbara Feder Ostrov Medscape - May 21, 2018   In Oregon and Denver, where marijuana is legal for recreational use, activists are now pushing toward a psychedelic frontier: “magic mushrooms.” Groups in both states are sponsoring ballot measures that would eliminate criminal penalties for possession of the mushrooms whose active ingredient, psilocybin, can cause hallucinations, euphoria and changes in perception. They point to research showing that psilocybin might be helpful for people suffering from depression or anxiety. “We don’t want individuals to lose their freedom over something that’s natural and has health benefits,” said Kevin Matthews, the campaign director [...]

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The Ethics of Taking the Drugs You Study. Should psychedelic scientists trip on the drugs they research?, Shayla LOVE, May 14  2019

The Ethics of Taking the Drugs You Study Should psychedelic scientists trip on the drugs they research? Shayla LOVE May 14  2019 From 1960 to 1962, the Harvard Psilocybin Project conducted unconventional experiments, like giving psilocybin to prison inmates to see if it would reduce recidivism, or doling it out to theology students to provoke a religious experience. Led by Timothy Leary and Richard Alpert, their goal was to test the potential applications of the active ingredient in magic mushrooms. Leary was a clinical psychologist and professor at Harvard. After taking mushrooms in 1960, he “declared that he learned more in the following five hours [...]

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Psychiatry might need some psychedelic therapy, Matthew W. Johnson, 2018

Psychiatry might need some psychedelic therapy Matthew W. Johnson International Review of Psychiatry, Institute of Psychiatry and Johns Hopkins University, 2018, 30, 4, 285-290. https://doi.org/10.1080/09540261.2018.1509544   EDITORIAL Psychiatry might need some psychedelic therapy In historical and modern-day studies, psychedelic drugs have shown promise in managing a variety of psychiatric disorders, but their medical use has often raised controversies. The controversies have related to social, political, and legal challenges. History Although anthropological evidence suggests that classic psychedelic drugs (hereafter, ‘psychedelics’) have been used by various indigenous peoples as sacraments and healing agents before recorded history, in the mid-twentieth century they came to occupy a place at the cutting edge of [...]

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Can psychedelics be the treatment for the crisis in psychopharmacology ?, Genís Ona & José Carlos Bouso, 2019

Can psychedelics be the treatment for the crisis in psychopharmacology ? Genís Ona, José Carlos Bouso ICEERS Foundation, Preprint · January 2019 DOI: 10.20944/preprints201901.0249.v1 Keywords : Mental health, psychedelics, psychopharmacology, psychiatry, innovative 1. Introduction For the past few years, we have been witnessing a crisis in the field of psychopharmacology. Generally, it takes a decade and up to a billion dollars in investment to get a drug on the market. Furthermore, the majority of new drugs are ruled out during the pre-clinical phase. Less than 20% of the selected drugs make it to Phase-III evaluation involving humans. Drug development has never been an easy task. However, [...]

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Should addiction researchers be interested in psychedelic science ?, Stephen Bright et al., 2017 ,

EDITORIAL Should addiction researchers be interested in psychedelic science ? Stephen Bright, Martin Williams & David Caldicott Australasian Professional Society on Alcohol and other Drugs, Drug and Alcohol Review, 2017 DOI: 10.1111/dar.12544   As recently noted by Strauss, Bright and Williams [1], while much of the Western world has been experiencing a renaissance in research into ‘psychedelic science’ over the past decade [2], there has been no such research conducted in Australia. In Europe and the USA, studies have been conducted into lysergic acid diethylamide (LSD) that have improved our understanding of brain function [3] and reduced existential anxiety associated with dying [4], while psilocybin-assisted psychotherapy has [...]

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Disruptive Psychopharmacology, Jama Psychiatry, June 2019

Disruptive Psychopharmacology Boris D. Heifets, MD, PhD1; Robert C. Malenka, MD, PhD2 JAMA Psychiatry. Published online June 26, 2019. doi:10.1001/jamapsychiatry.2019.1145 The paucity of medications with novel mechanisms for the treatment of mental illnesses combined with the delayed response to currently available medications has led to great excitement about the potential therapeutic utility of previously demonized drugs, which offer the hope of generating rapid symptom reductions in some of the sickest patients. Within the past 2 years, the US Food and Drug Administration approved esketamine for treatment-resistant depression and 2 compounds that are still on the US Drug Enforcement Administration’s most restrictive schedule, 3,4-methylenedioxymethamphetamine (MDMA) and psilocybin, [...]

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Cannabis récréatif et politique: oui ou non, Emmanuel Macron est-il contre sa légalisation ?, le Blog de jean-Yves NAU, 19 juin 2019

Cannabis récréatif et politique: oui ou non, Emmanuel Macron est-il contre sa légalisation ? 19 juin 2019 jean-yves nau addictions, alcoolisme, Argent, législatif, Médecine, Polémique, Politique, Pouvoir, Risques (réduction des), tabagisme, Toxicomanies Étiquettes : L'Obs https://jeanyvesnau.com/2019/06/19/cannabis-recreatif-et-politique-oui-ou-non-emmanuel-macron-est-il-contre-sa-legalisation/   Bonjour Pour un peu le journaliste se lasserait. Des députés de quatre groupes politiques (dont certains macronistes) prônent désormais ouvertement une « légalisation contrôlée » du cannabis – et ce dans une proposition de loi transmise de mardi 18 juin à la presse. Ce texte sera officiellement déposé ce 19 juin. Signataires : François-Michel Lambert, Sylvia Pinel, Paul Molac, Jean-Michel Clément, Jeanine Dubié, Frédérique Dumas, François Pupponi (Libertés et territoires), Delphine Bagarry, Annie Chapelier, Hubert Julien-Laferrière, Pierre-Alain Raphan [...]

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L’appel de 70 médecins, élus, économistes : « Pourquoi nous voulons légaliser le cannabis », L’Obs, 19 juin 2019

L’appel de 70 médecins, élus, économistes : « Pourquoi nous voulons légaliser le cannabis » La une de « l’Obs », du 20 au 26 juin 2019. (« L’Obs ») EXCLUSIF. Dénonçant la faillite de la politique de répression, 70 personnalités – Glucksmann, Jadot, Kouchner… – appellent à la légalisation du cannabis. Par L'Obs Publié le 19 juin 2019 à 06h30 En matière de cannabis, le tout-répressif ne marche pas. Alors sortons de cette politique coûteuse et inefficace. « L’Obs » lance avec plus de 70 économistes, médecins, politiques un appel à une légalisation encadrée. Objectifs prioritaires : la protection des mineurs, la sécurité [...]

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Cannabis thérapeutique : l’activisme injustifiable de l’Académie nationale de pharmacie, Blog de Jean-Yves NAU, 18 juin 2019

excellent article de Jean-Yves Nau, avec deux réponses "pertinentes" du Pr Nicolas Authier et du Dr William Lowenstein Cannabis thérapeutique : l’activisme injustifiable de l’Académie nationale de pharmacie 18 juin 2019 jeanyvesnau addictions, Déontologie, Douleur, Médecine, médicament, Pharmacie, Polémique, Politique, Pouvoir, Risques (réduction des), santé publique, Toxicomanies Étiquettes : European Respiratory Journal, The Conversation, The Lancet https://jeanyvesnau.com/2019/06/18/cannabis-therapeutique-lactivisme-injustifiable-de-lacademie-nationale-de-pharmacie/ Bonjour Pour un peu on se gausserait. Sur le mode « l’Académie abuse la galerie ». Les faits : un communiqué de presse daté du 17 juin de l’Académie nationale de pharmacie : « Cannabis ‘’thérapeutique’’ : une appellation abusive et dangereuse ». Cette institution entend aujourd’hui « mettre en garde [...]

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