CBD User's Guide Project CBD On March 13, 2018 (Updated on March 25, 2019) https://www.projectcbd.org/how-to/cbd-users-guide Project CBD has created a beginner’s guide for cannabidiol & cannabis therapeutics to address key questions of CBD users. A Beginner’s Guide to CBD & Cannabis Therapeutics In 2009, a handful of CBD-rich cannabis strains were discovered serendipitously in Northern California, America’s cannabis breadbasket, where certified patients could access medical marijuana legally. Thus began a great laboratory experiment in democracy involving CBD-rich cannabis therapeutics. The advent of whole plant CBD-rich oil as a grassroots therapeutic option has changed the national conversation about cannabis. It’s no longer a question of whether [...]
Lire la suiteCBD & Cannabis Dosage Guide Martin A. Lee On May 16, 2018 (Updated on April 1, 2019) https://www.projectcbd.org/how-to/cbd-dosage-guide High dose? Low dose? CBD? THC? Optimizing one's therapeutic use of cannabis may take some experimentation. It can be relatively easy to experience medical benefits from cannabis. A puff or two of tetrahydrocannabinol (THC)-rich flower can do the trick for a lot of people. Smoking marijuana, however, is not the be-all and end-all of cannabis therapeutics. There are many ways to experience the medical benefits of cannabis, and some of them are even non-intoxicating. In recent years, the advent of potent cannabis oil concentrates, non-intoxicating cannabidiol (CBD) products, [...]
Lire la suiteMedical cannabis and mental health : A guided systematic review, Zach Walsh, Raul Gonzalez, Kim Crosby, Michelle S. Thiessen, Chris Carroll, Marcel O. Bonn-Miller Clinical Psychology Review, 2017, 51, 15-29. Doi : 10.1016/j.cpr.2016.10.002 a b s t r a c t This review considers the potential influences of the use of cannabis for therapeutic purposes (CTP) on areas of interest to mental health professionals, with foci on adult psychopathology and assessment. We identified 31 articles relating to the use of CTP and mental health, and 29 review articles on cannabis use and mental health that did not focus on use for therapeutic purposes. Results reflect the [...]
Lire la suiteBibliographie : Interactions et antagonisme THC - CBD Docteur Christian SUEUR, GRECC, novembre 2019. Les interactions entre le THC et le CBD sur le système endocannabinoide, quant aux effets psychotomimetic (production de "symptomes psychotiques") sont opposés : là où le THC produit préférentiellement de l'anxiété, et des effets "psychotisants", le CBD est plutôt anxiolytique et "antipsychotique". Ces deux phytocannabinoïdes sont "antagonistes", et contribuent, parmi d'autres inter-relations entre les phytocannabinoïdes, les terpènes et les flavonoïdes composant le cannabis, aux "effets d'entourage" fondamentaux, tout autant quant à la production "d'effets indésirables" et de risques pour la santé mentale du consommateur, que dans le cadre de [...]
Lire la suiteMedical use of cannabis products. Lessons to be learned from Israel and Canada J. Ablin, P.A. Ste-Marie, M. Schäfer, W. Häuser, M.-A. Fitzcharles Der Schmerz, 2016, 1-10 DOI 10.1007/s00482-015-0083-4 © Deutsche Schmerzgesellschaft e.V. Published by Springer-Verlag Berlin Heidelberg - all rights reserved 2015 Abstract Introduction : The German government intends to reduce the barriers for the medical use of cannabis products. A discussion on the indications and contraindications of the medical use of cannabis and on the changes of the regulatory framework has already begun in Germany. It is useful to draw from the experiences of other countries with a more liberal medical use of cannabis. Methods [...]
Lire la suiteAn update on cannabis use disorder with comment on the impact of policy related to therapeutic and recreational cannabis use Alan J. Budney,· Michael J. Sofis,· Jacob T. Borodovsky European Archives of Psychiatry and Clinical Neuroscience, 2019 https://doi.org/10.1007/s00406-018-0976-1 © Springer-Verlag GmbH Germany, part of Springer Nature 2019 Abstract : Confusion and controversy related to the potential for cannabis use to cause harm, or alternatively to provide benefit, continues globally. This issue has grown in intensity and importance with the increased recognition of the public health implications related to the escalation of the legalization of cannabis and cannabinoid products. This selective overview and commentary attempt to succinctly [...]
Lire la suiteEffects of endocannabinoid neurotransmission modulators on brain stimulation reward Styliani Vlachou, George G. Nomikos & George Panagis Psychopharmacology, 2006, 188, 293–305 Doi : 10.1007/s00213-006-0506-0 Abstract Rationale : The endogenous cannabinoid system is responsive to the neurobiological actions of Δ9-tetrahydrocannabinol (THC) and other cannabinoid ligands. While numerous studies have focused on the behavioral and pharmacological effects of THC and cannabinoid agonists in experimental animals, most recent work focuses on compounds that modulate endocannabinoid neurotransmission. However, the relevant studies concerning the ability of endocannabinoid modulators to modify reward processes in experimental animals remain rather scarce. Objectives : The present study examined the effects of drugs modulating endocannabinoid neurotransmission on [...]
Lire la suiteSafety and Efficacy of Medical Cannabis in Fibromyalgia Iftach Sagy, Lihi Bar-Lev Schleider, Mahmoud Abu-Shakra and Victor Novack Journal of Clinical Medicine, 2019, 8, 807 doi : 10.3390/jcm8060807 Abstract : Background : Chronic pain may be treated by medical cannabis. Yet, there is scarce evidence to support the role of medical cannabis in the treatment of fibromyalgia. The aim of the study was to investigate the characteristics, safety, and eectiveness of medical cannabis therapy for fibromyalgia. Methods : A prospective observational study with six months follow-up period based on fibromyalgia patients who were willing to answer questionnaire in a specialized medical cannabis clinic between 2015 and 2017. Results : Among the [...]
Lire la suiteWhat Are the Benefits of CBD ? More than 60 percent of CBD users were taking it for anxiety, according to a survey of 5,000 people. Does it help? THE NEW YORK TIMES, By Dawn MacKeen Published Oct. 16, 2019 https://www.nytimes.com/2019/10/16/style/self-care/cbd-oil-benefits.html Credit...Photo Illustration by The New York Times; Shutterstock The CBD industry is flourishing, conservatively projected to hit $16 billion in the United States by 2025. Already, the plant extract is being added to cheeseburgers, toothpicks and breath sprays. More than 60 percent of CBD users have taken it for anxiety, according to a survey of 5,000 people, conducted by the Brightfield Group, a cannabis market [...]
Lire la suiteFDA, FTC warn company marketing unapproved cannabidiol products with unsubstantiated claims to treat teething and ear pain in infants, autism, ADHD, Parkinson’s and Alzheimer’s disease FDA is also working quickly to evaluate regulatory policies related to cannabis and cannabis-derived ingredients like CBD October 22, 2019 https://www.fda.gov/news-events/press-announcements/fda-ftc-warn-company-marketing-unapproved-cannabidiol-products-unsubstantiated-claims-treat-teething Today, the U.S. Food and Drug Administration and the Federal Trade Commission posted a joint warning letter to Rooted Apothecary LLC, of Naples, Florida, for illegally selling unapproved products containing cannabidiol (CBD) online with unsubstantiated claims that the products treat teething pain and ear aches in infants, autism, attention-deficit/hyperactivity disorder (ADHD), as well as Parkinson’s and Alzheimer’s disease, [...]
Lire la suite