Étiquette : LSD

Psychedelic drug use in healthy individuals : A review of benefits, costs, and implications for drug policy, James W.B. Elsey, 2017

Psychedelic drug use in healthy individuals : A review of benefits, costs, and implications for drug policy James W.B. Elsey Drug Science, Policy and Law, 2017, 3, 1-11 sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/2050324517723232   Abstract The potential of psychedelic drugs in the treatment of mental health problems is increasingly being recognized. However, relatively little thrust has been given to the suggestion that individuals without any mental health problems may benefit from using psychedelic drugs, and that they may have a right to do so. This review considers contemporary research into the use of psychedelic drugs in healthy individuals, including neurobiological and subjective effects. In line with findings suggesting positive [...]

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The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future, Robin L Carhart-Harris and Guy M Goodwin, 2017

The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future Robin L Carhart-Harris and Guy M Goodwin Neuropsychopharmacology, 2017, 42, 2105–2113 doi:10.1038/npp.2017.84; published online 17 May 2017 Plant-based psychedelics, such as psilocybin, have an ancient history of medicinal use. After the first English language report on LSD in 1950, psychedelics enjoyed a short-lived relationship with psychology and psychiatry. Used most notably as aids to psychotherapy for the treatment of mood disorders and alcohol dependence, drugs such as LSD showed initial therapeutic promise before prohibitive legislature in the mid-1960s effectively ended all major psychedelic research programs. Since the early 1990s, there has been a steady [...]

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Beyond LSD : A Broader Psychedelic Zeitgeist during the Early to Mid-20th Century, Jacob S. Aday et al., 2019

Beyond LSD : A Broader Psychedelic Zeitgeist during the Early to Mid-20th Century Jacob S. Aday, M.S. , Emily K. Bloesch, Ph.D. , and Christopher C. Davoli, Ph.D. Journal of Psychoactive Drugs, 2019 https://doi.org/10.1080/02791072.2019.1581961   ABSTRACT During the 1950s and 1960s, there was a tremendous surge in research into the effects of psychedelic drugs. When discussing this period of research, the discovery of the psychoactive properties of LSD in 1943 is often presented as the main, and sometimes only, driving force of the boom in research. This “Great Person,” or “Great Chemical,” historiographical lens fails to acknowledge other factors that were fundamental in setting the stage [...]

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Psychedelic-assisted therapy for anxiety and depression in the face of death : A critical review with an anthropological lens, Jenna VARLEY, 2019

Psychedelic-assisted therapy for anxiety and depression in the face of death:  A critical review with an anthropological lens Jenna VARLEY Journal of Psychedelic Studies, 2019,  3, (1), 14–18. DOI: 10.1556/2054.2019.005   Psychedelics have been investigated for their therapeutic applications in end-of-life care as early as 1960. Recently, there have been four main groups conducting clinical trials for either lysergic acid diethylamide or psilocybin for the treatment of anxiety and depression in patients with terminal illnesses. The recent trials have higher methodological quality and demonstrate the profound impact of psychedelics for this particular patient presentation. However, a number of gaps, including understanding the meaning of death [...]

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Intercultural, intermolecular : An ethnobotanical examination of the potential therapeutic value of LSD for the treatment of depression, Karsten FATUR, 2019

Intercultural, intermolecular : An ethnobotanical examination of the potential therapeutic value of LSD for the treatment of depression Karsten FATUR Journal of Psychedelic Studies, 2019, 3, (1), 32–34. DOI: 10.1556/2054.2019.002   Lysergic acid diethylamide holds great therapeutic potential in the treatment of depression, although currently illegal in many parts of the world and seen as a recreational drug. An intercultural ethnobotanical examination of plant substances with similar chemical profiles and effects displays the true potential value of this substance and justifies an increased focus on clinical trials and studies involving it. Keywords : psychedelic, LSD, ayahuasca, depression, serotonin   Despite its current status as an illegal substance, lysergic [...]

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Neural correlates of the LSD experience revealed by multimodal neuroimaging, Robin L. Carhart-Harris et al., 2016

Neural correlates of the LSD experience revealed by multimodal neuro-imagerie Robin L. Carhart-Harris, Suresh Muthukumaraswamy, Leor Roseman, Mendel Kaelen, Wouter Droog, Kevin Murphy, Enzo Tagliazucchi, Eduardo E. Schenberg, Timothy Nest, Csaba Orban, Robert Leech, Luke T. Williams, Tim M. Williams, Mark Bolstridge, Ben Sessa, John McGonigle, Martin I. Sereno, David Nichols, Peter J. Hellyer, Peter Hobden, John Evans, Krish D. Singh, Richard G. Wise, H. Valerie Curran, Amanda Feilding, and David J. Nutt PNAS (Proceedings of The National Academy of Sciences of the USA), 2016, 113, 17, 4853-4858 www.pnas.org/cgi/doi/10.1073/pnas.1518377113   Abstract Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human [...]

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For the First Time, Scientists Have Imaged the Brain on LSD, Victoria TURK, Vice, April 11, 2016

For the First Time, Scientists Have Imaged the Brain on LSD The scientists hope their long-awaited study on LSD in humans will open the floodgates to further research into psychedelics. Victoria TURK, April 11, 2016 https://www.vice.com/en_us/article/bmvm3w/for-the-first-time-scientists-have-imaged-the-brain-on-lsd Researcher, drug policy reformer, and Countess of Wemyss Amanda Feilding made a promise to Albert Hofmann, the "father of LSD," after meeting him in the 90s: She would carry out scientific research with his "problem child" on human subjects by his 100th birthday in 2006. A study published on Monday makes good on that vow, albeit ten years late: For the first time, researchers have imaged the human brain [...]

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LSD Brings Your Brain to the Edge of Chaos, Shayla Love, Vice, Mars 2, 2018

LSD Brings Your Brain to the Edge of Chaos This new LSD study is like an acid trip all on its own. This story was first published by Tonic, VICE's health site. You can now find the same great health content right here at vice.com. One Saturday in 1964, neurologist Oliver Sacks took a bit of amphetamines, LSD, a “touch” of cannabis, faced a white wall in his home, and said “I want to see indigo now—now!” “And then,” he wrote in the New Yorker in 2012, “as if thrown by a giant paintbrush, there appeared a huge, trembling, pear-shaped blob of the [...]

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Perceptions of the medicinal value of hallucinogenic drugs among college students, Jared I. WILDBERGER et al., 2017

Perceptions of the medicinal value of hallucinogenic drugs among college students JARED I. WILDBERGER, CASSANDRA N. JOHN and ROBERT M. HALLOCK Journal of Psychedelic Studies, 2017, 1(2), pp. 50–54 DOI: 10.1556/2054.01.2017.008   Background : This survey examined perceptions among college students about the potential medicinal benefits of hallucinogenic drugs. Current research and potential benefits include an ability to help anxiety, post-traumatic stress disorder, and addiction with hallucinogen-assisted psychotherapy. Methods : We devised and administered a survey on 124 students at two college campuses, one small private college in the mid-Atlantic and one medium-sized public university in the Midwest of the United States. Results: Responses were similar [...]

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Effects of Schedule I drug laws on neuroscience research and treatment innovation, Nutt D.J. et al., 2013

Effects of Schedule I drug laws on neuroscience research and treatment innovation. Nutt D.J., King L.A., Nichols D.E. Nature Reviews Neuroscience, 2013, 14, 577-585 DOI : 10.1038/nrn3530   Abstract Many psychoactive drugs are used recreationally, particularly by young people. This use and its perceived dangers have led to many different classes of drugs being banned under national laws and international conventions. Indeed, the possession of cannabis, 3,4‑methylenedioxy- N‑methyl-amphetamine (MDMA; also known as ecstasy) and psychedelics is stringently regulated. An important and unfortunate outcome of the controls placed on these and other psychoactive drugs is that they make research into their mechanisms of action and potential therapeutic [...]

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