Étiquette : cannabis

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis, Mohamed M. Radwan et al., 2021

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis Mohamed M. Radwan, Suman Chandra, Shahbaz Gul and Mahmoud A. ElSohly Molecules, 2021, 26, 2774. Doi : 10.3390/molecules26092774   Abstract : Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during the early 19th century. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type constituents. More than 500 compounds have been reported from C. sativa, of which 125 cannabinoids have been isolated and/or identified as cannabinoids. Cannabinoids are C21 terpeno phenolic compounds specific to Cannabis. The non-cannabinoid constituents include: non-cannabinoid phenols, flavonoids, terpenes, alkaloids and others. This review discusses [...]

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Cannabis-related diagnosis in pregnancy and adverse maternal and infant outcomes, Gretchen Bandoli et al., 2021

Cannabis-related diagnosis in pregnancy and adverse maternal and infant outcomes Gretchen Bandoli, Laura Jelliffe-Pawlowski, Benjamin Schumacher, Rebecca J. Baer, Jennifer N. Felder, Jonathan D. Fuchs, Scott P. Oltman, Martina A. Steurer, Carla Marienfeld Drug and Alcohol Dependence, 2021, 225, 108757. doi : 10.1016/j.drugalcdep.2021.108757   Abstract Background: Cannabis use and cannabis use disorders are increasing in prevalence, including among pregnant women. The objective was to evaluate the association of a cannabis-related diagnosis (CRD) in pregnancy and adverse maternal and infant outcomes. Methods: We queried an administrative birth cohort of singleton deliveries in California between 2011-2017 linked to maternal and infant hospital discharge records. We [...]

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PROPOSITION DE LOI relative à la lutte contre le commerce illégal de drogues, ASSEMBLÉE NATIONALE, Enregistré à la Présidence de l’Assemblée nationale le 18 mai 2021.

N° 4173 _____ ASSEMBLÉE NATIONALE CONSTITUTION DU 4 OCTOBRE 1958 QUINZIÈME LÉGISLATURE Enregistré à la Présidence de l’Assemblée nationale le 18 mai 2021. PROPOSITION DE LOI relative à la lutte contre le commerce illégal de drogues, (Renvoyée à la commission des affaires sociales, à défaut de constitution d’une commission spéciale dans les délais prévus par les articles 30 et 31 du Règlement.) présentée par Mesdames et Messieurs Éric COQUEREL, Jean-Félix ACQUAVIVA, Ugo BERNALICIS, Alexis CORBIÈRE, Elsa FAUCILLON, Hubert JULIEN-LAFERRIÈRE, François-Michel LAMBERT, Jean-Baptiste MOREAU, Danièle OBONO, Matthieu ORPHELIN, Richard RAMOS, Jean-Hugues RATENON, Muriel RESSIGUIER, Bénédicte TAURINE, Michèle VICTORY, Patrick VIGNAL, députés. EXPOSÉ DES MOTIFS MESDAMES, MESSIEURS, Cette proposition de loi se donne pour objectif de [...]

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Absence of Entourage : Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors, Marina Santiago et al., 2019

Absence of Entourage : Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Functional Activity of Δ9-THC at Human CB1 and CB2 Receptors Marina Santiago, Shivani C. Arnold, Iain S., McGregor and Mark Connor Cannabis and Cannabinoid Research, 2019, Vol. 4, No. 3 doi : 10.1089/can.2019.0016 Abstract Introduction: Compounds present in Cannabis sativa such as phytocannabinoids and terpenoids may act in concert to elicit therapeutic effects. Cannabinoids such as Δ9-tetrahydrocannabinol (Δ9-THC) directly activate cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2); however, it is not known if terpenoids present in Cannabis also affect cannabinoid receptor signaling. Therefore, we examined six common terpenoids alone, [...]

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Les recommandations de NORML France à la Mission d’Information Cannabis de l’Assemblée Nationale, par Le Collectif, 20 Avril, 2021 |

Les recommandations de NORML France à la Mission d’Information Cannabis de l’Assemblée Nationale NORML France, par Le Collectif | Avr 20, 2021 | https://www.norml.fr/nos-recommandations-mission-information-cannabis-an/ Nos propositions ont été adressées en février de cette année à la Mission d’information “Réglementation et impact des différents usages du cannabis” de l’Assemblée Nationale. Ce même document de 22 recommandations sera envoyé par email à l’ensemble de nos députés et sénateurs cette semaine. Vous pouvez le retrouver dans sa version complète comme dans sa version courte sur cette page.   CANNABIS : VERS UNE RÉGULATION BÉNÉFIQUE AUX USAGERS ET À LA SOCIÉTÉ. 📗 Téléchargez la note complète Cette note est le fruit d’un [...]

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Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment, Anna Stasiłowicz et al., 2021

Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment Anna Stasiłowicz, Anna Tomala, Irma Podolak and Judyta Cielecka-Piontek International Journal of Molecular Sciences, 2021, 22, 778. Doi : 10.3390/ijms22020778 Abstract : Cannabis sativa L. turned out to be a valuable source of chemical compounds of various structures, showing pharmacological activity. The most important groups of compounds include phytocannabinoids and terpenes. The pharmacological activity of Cannabis (in epilepsy, sclerosis multiplex (SM), vomiting and nausea, pain, appetite loss, inflammatory bowel diseases (IBDs), Parkinson’s disease, Tourette’s syndrome, schizophrenia, glaucoma, and coronavirus disease 2019 (COVID-19)), which has been proven so far, results [...]

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Cannabinoid Hyperemesis Syndrome : A Case Report and Discussion Regarding Patients with Concurrent Disorders, Stephen Lee-Cheong et al., 2020,

Cannabinoid Hyperemesis Syndrome : A Case Report and Discussion Regarding Patients with Concurrent Disorders Stephen Lee-Cheong, Amrita Grewal, Lukas Hestvik, Reza Rafizadeh, and Christian Schütz The Canadian Journal of Hospital Pharmacy, 2020, 73, (4), 290-293   INTRODUCTION In October 2018, Canada legalized the nonmedical use of cannabis. Usage has traditionally been high in Canada, and after legalization, self-reported use increased from 14% to 18%.1 Given this increased usage, it is important to understand the adverse effects of cannabis. Here, we focus on a less well-recognized consequence, cannabinoid hyperemesis syndrome (CHS), first described in 2004.2 It may be seen more often in jurisdictions where cannabis is legalized; [...]

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Cannabis : An Emerging Treatment for Common Symptoms in Older Adults, Kevin H. Yang et al., Medscape.com, 2021

Cannabis : An Emerging Treatment for Common Symptoms in Older Adults Kevin H. Yang, BS; Christopher N. Kaufmann, PhD, MHS; Reva Nafsu, LVN; Ella T. Lifset; Khai Nguyen, MD, MHS; Michelle Sexton, ND; Benjamin H. Han, MD, MPH; Arum Kim, MD; Alison A. Moore, MD, MPH Journal of American Geriatric Society, 2021, 69, (1), 91-97. https://www.medscape.com/viewarticle/945238   Abstract and Introduction Abstract Background/Objectives: Use of cannabis is increasing in a variety of populations in the United States; however, few investigations about how and for what reasons cannabis is used in older populations exist. Design: Anonymous survey. Setting: Geriatrics clinic. Participants: A total of 568 adults 65 years and older. Intervention: Not applicable. Measurements: [...]

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High-Potency Cannabis Products Linked to Suicidality, Doug Brunk, Medscape.com, February 22, 2021

High-Potency Cannabis Products Linked to Suicidality Doug Brunk Medscape Medical News © 2021 WebMD, LLC February 22, 2021 Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. In the days since recreational sales of marijuana became legal in Colorado in January 2014, concerning trends have emerged among the state's young cannabis users. Dr Paula Riggs According to a report from the Rocky Mountain High Intensity Drug Trafficking Area, between 2014 and 2017, the number of suicides positive for marijuana increased 250% among those aged 10-19 years (from 4 to 14) and 22% among those aged 20 and older (from 118 to 144). "Other states are seeing something [...]

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Association of Recreational Cannabis Legalization With Maternal Cannabis Use in the Preconception, Prenatal, and Postpartum Periods, Kara R. Skelton et al., 2021

Original Investigation | Substance Use and Addiction Association of Recreational Cannabis Legalization With Maternal Cannabis Use in the Preconception, Prenatal, and Postpartum Periods Kara R. Skelton, PhD; Amelie A. Hecht, PhD; Sara E. Benjamin-Neelon, PhD, JD JAMA Network Open, 2021, 4, (2), 1-12, e210138. doi : 10.1001/jamanetworkopen.2021.0138   Abstract IMPORTANCE : Recent studies have revealed increases in population-level cannabis use after legalization of recreational cannabis. However, the association of cannabis legalization with maternal cannabis use during important life stages remains unknown. OBJECTIVE : To investigate the association of legalization of recreational cannabis with maternal cannabis use during the preconception, prenatal, and postpartum periods. DESIGN, SETTING, AND PARTICIPANTS : This repeated [...]

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