Catégorie : Botanique

A reliable and validated LC-MS/MS method for the simultaneous quantification of 4 cannabinoids in 40 consumer products, Qingfang Meng et al., 2018

A reliable and validated LC-MS/MS method for the simultaneous quantification of 4 cannabinoids in 40 consumer products Qingfang Meng, Beth Buchanan, Jonathan Zuccolo, Mathieu-Marc Poulin, Joseph Gabriele, David Charles Baranowski PLoS ONE, 2018, 13, (5), e0196396. https://doi.org/10.1371/journal.pone.0196396   Abstract In the past 50 years, Cannabis sativa (C. sativa) has gone from a substance essentially prohibited worldwide to one that is gaining acceptance both culturally and legally in many countries for medicinal and recreational use. As additional jurisdictions legalize Cannabis products and the variety and complexity of these products surpass the classical dried plant material, appropriate methods for measuring the biologically active constituents is paramount to ensure [...]

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Isolation of a High Affinity Cannabinoid for Human CB1 Receptor from a Medicinal Cannabis Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol, Pasquale Linciano et al., 2019

Isolation of a High Affinity Cannabinoid for Human CB1 Receptor from a Medicinal Cannabis Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol Pasquale Linciano, Cinzia Citti, Livio Luongo, Carmela Belardo, Sabatino Maione, Maria Angela Vandelli, Flavio Forni, Giuseppe Gigli, Aldo Laganà, Carmela Maria Montone, Giuseppe Cannazza Journal of Natural Products, 2019 Dec 31. doi: 10.1021/acs.jnatprod.9b00876.   Abstract The butyl homologues of Δ9-tetrahydrocannabinol, Δ9-tetrahydrocannabutol (Δ9-THCB), and cannabidiol, cannabidibutol (CBDB), were isolated from a medicinal Cannabis sativa variety (FM2) inflorescence. Appropriate spectroscopic and spectrometric characterization, including NMR, UV, IR, ECD, and HRMS, was carried out on both cannabinoids. The chemical structures and absolute configurations of the isolated cannabinoids were [...]

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Cannabis Systematics at the Levels of Family, Genus, and Species, John M. McPartland, 2018

Cannabis Systematics at the Levels of Family, Genus, and Species John M. McPartland Cannabis and Cannabinoid Research, 2018, Volume 3.1, 203- Doi : 10.1089/can.2018.0039   Abstract New concepts are reviewed in Cannabis systematics, including phylogenetics and nomenclature. The family Cannabaceae now includes Cannabis, Humulus, and eight genera formerly in the Celtidaceae. Grouping Cannabis, Humulus, and Celtis actually goes back 250 years. Print fossil of the extinct genus Dorofeevia (=Humularia) reveals that Cannabis lost a sibling perhaps 20 million years ago (mya). Cannabis print fossils are rare (n = 3 worldwide), making it difficult to determine when and where she evolved. A molecular clock analysis with chloroplast [...]

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Myorelaxant Effect of Transdermal Cannabidiol Application in Patients with TMD : A Randomized, Double-Blind Trial, Aleksandra Nitecka-Buchta et al., 2019

Myorelaxant Effect of Transdermal Cannabidiol Application in Patients with TMD : A Randomized, Double-Blind Trial Aleksandra Nitecka-Buchta, Anna Nowak-Wachol, KacperWachol, KarolinaWalczynska-Dragon, Paweł Olczyk, Olgierd Batoryna, Wojciech Kempa and Stefan Baron Journal of Clinical Medicine, 2019, 8, 188, 1-17. doi : 10.3390/jcm8111886 Abstract Background : The healing properties of cannabidiol (CBD) have been known for centuries. In this study, we aimed to evaluate the efficiency of the myorelaxant effect of CBD after the transdermal application in patients with myofascial pain. Methods : The Polish version of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD Ia and Ib) was used. A total of 60 patients were enrolled [...]

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Cannabis Oil : chemical evaluation of an upcoming cannabis-based medicine, Luigi L. Romano, Arno Hazekamp, 2013

Cannabis Oil : chemical evaluation of an upcoming cannabis-based medicine Luigi L. Romano, Arno Hazekamp Cannabinoids, 2013, 1, (1), 1-11 © International Association for Cannabinoid Medicines   Abstract Concentrated cannabis extracts, also known as Cannabis oils because of their sticky and viscous appearance, are becoming increasingly popular among self-medicating patients as a claimed cure for cancer. In general, preparation methods for Cannabis oils are relatively simple and do not re-quire particular instruments. The most well-known example of such a product is called ‘Simpson oil’. The purpose of the extraction, often followed by a solvent evaporation step, is to make canna-binoids and other beneficial components such as [...]

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CBD Oil : An Introduction, Zoe Sigman, 2019

CBD Oil: An Introduction Zoe Sigman 2019 https://www.projectcbd.org/cbd-101/what-is-cbd-oil   Medical patients swear by it. Researchers are intrigued by it. Government regulators are flustered by it. And investors are head over heels for it. CBD oil is the It-Medicine of the moment. A few years ago, hardly anyone knew about CBD oil. Today there’s a huge demand for it. Millions of people are taking CBD oil as a health supplement. But what exactly is it? Where does it come from? How is it made? And what should you know before you buy it? Where Does CBD Oil Come From ? Cannabidiol (CBD) is one of more than 100 unique “cannabinoid” [...]

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« Heureusement qu’il y a l’herbe ! », Anne Coppel, Chimères, 2014

« Heureusement qu’il y a l’herbe ! » Anne Coppel ERES | « Chimères », 2014/1 N° 82 | pages 33 à 42 https://www.cairn.inforevue-chimeres-2014-1-page-33.htm « On ne trouve pas trace dans les livres, ni ailleurs, du nom de Govan- Eremetus, ni du pays d’Archaos où il régna, entre la fin des Temps- Barbares et le commencement des Temps-Barbares. Pourtant quelque chose manque là, à la fois dans le temps et dans l’espace. À ce tournant mal éclairé de l’histoire, il y a comme un trou, des événements postérieurs restent inexpliqués. Les coordonnées ne se rejoignent pas ; à partir d’un certain point on les [...]

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Il y a herbe et herbe, Michka Seeliger-Chatelain, Chimères, 2014

Il y a herbe et herbe Michka SEELIGER-CHATELAIN ERES | « Chimères », 2014/1 N° 82 | pages 43 à 48 https://www.cairn.inforevue-chimeres-2014-1-page-43.htm   Jean-Philippe Cazier : Vous dites que fumer de l’herbe vous a permis d’échapper à une forme de rationalité trop stricte. Est-ce que vous diriez que le cannabis a rendu possible, pour vous, un nouveau rapport au monde et à soi, de produire une forme de subjectivité ? M. : Le mot « cannabis » est encore plus vague que le mot « vin ». Il y a un monde entre le gros rouge de base et un grand cru élevé avec amour. Le [...]

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Textes – Recueil du Bon Plant, François Olivier Gagnon-Hébert, 2019

Textes - Recueil du Bon Plant François Olivier Gagnon-Hébert 2019   Titre : Pas de panique ! Le cannabis était là avant nous… et il le sera sûrement encore après nous.   Le cannabis, ce n’est pas le nom d’un poison, ni d’une drogue pharmaceutique. Ce n’est pas non plus un mot inventé par les politiciens pour faire peur ou pour influencer les résultats d’un concours de popularité à l’échelle du pays. Le cannabis peut être bien des choses pour bien des personnes, mais avant même d’être le démon incarné qui rend les mœurs légères, et avant même d’être le prochain remède holistique à tous les maux [...]

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An Overview of Galenic Preparation Methods for Medicinal Cannabis, Luigi Romano and Arno Hazekamp, 2018

An Overview of Galenic Preparation Methods for Medicinal Cannabis Luigi Romano and Arno Hazekamp Current Bioactive Compounds, 2018, 14, DOI: 10.2174/1573407214666180612080412   Abstract : In recent years, the Cannabis plant (Cannabis sativa L.) has been rediscovered as a source of new medicines around the world. Despite the fact that a number of registered medicines have been developed on the basis of purified cannabis components, there is a rapid increasing acceptance and use of cannabis in its herbal form. Licensed producers of high quality cannabis plants now operate in various countries including The Netherlands, Canada, Israel, and Australia, and in many US states. The legal availability of [...]

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