Fibromyalgia and the endocannabinoid system John M. McPartland in Fibromyalgia syndrome : A practitioner’s guide to treatment, chapter 11, 2010, 263-277. Doi : 10.1016/B978-0-443-06936-9.00011-1 CHAPTER CONTENTS Introduction . . . . . . . . . . . . . . . 263 Cannabis and cannabinoid receptors . . 264 Endocannabinoids and their enzymes . 266 Nociception and pain . . . . . . . . . . 266 Around the edges of fibromyalgia . . . . 269 Enhancing the eCB system . . . . . . . 270 Other approaches . . . . . . . . . . . . 272 Conclusions . . . . [...]
Lire la suiteCannabinoids, Pain, and Opioid Use Reduction : The Importance of Distilling and Disseminating Existing Data Kent E. HUTCHISON, Sarah L. HAGERTY, Jeffrey GALINKIN, Angela D. BRYAN, L. Cinnamon BIDWELL Cannabis and Cannabinoid Research, 2019, 4, (3), 158-164. Doi : 10.1089/can.2018.0052 Abstract The high prevalence of chronic pain conditions combined with an over-reliance on opioid prescriptions has resulted in an opioid epidemic and a desperate need for solutions. There is some debate about whether cannabis might play a role in addressing chronic pain conditions as well as the opioid epidemic. Recent surveys suggest that a large number of people are using cannabis as a treatment for [...]
Lire la suiteLe Petit Livre du Cannabis Médical Nicolas Authier, Editions First, 2021, 149 pages Sommaire Petit livre Cannabis Médical - N Authier
Lire la suitePotential Pharmacokinetic Drug-Drug Interactions between Cannabinoids and Drugs Used for Chronic Pain Marta Vázquez, Natalia Guevara, Cecilia Maldonado, Paulo Cáceres Guido, and Paula Schaiquevich Hindawi, BioMed Research International, 2020, Article ID 3902740, 9 pages Doi : 10.1155/2020/3902740 Choosing an appropriate treatment for chronic pain remains problematic, and despite the available medication for its treatment, still, many patients complain about pain and appeal to the use of cannabis derivatives for pain control. However, few data have been provided to clinicians about the pharmacokinetic drug-drug interactions of cannabinoids with other concomitant administered medications. Therefore, the aim of this brief review is to assess the interactions between [...]
Lire la suiteMedical Cannabis Use Rising Among Older Adults Pauline Anderson Medscape Medical News ©March 22, 2021 More individuals are using medical cannabis, but the increase appears to be more pronounced among seniors, new research suggests. Results of a large Canadian survey study show that the proportion of older users among total users increased from 17.6% before 2017 to 26.7% in 2018 and 31.2% in 2019. The proportion of older users was 22.7% in 2020, but there were fewer participants in this latest sample (8869 in 2019 and 5644 in 2020). The majority of older respondents reported that they use cannabis to relieve pain and prefer cannabidiol [...]
Lire la suiteThe Reemergence of Ketamine for Treatment in Critically Ill Adults Kimberly P. Hurth, Kristen B. Thomas, Michael A. Rudoni Critical Care Medicine, 2020,1-13. Doi : 10.1097/CCM.0000000000004335 Objectives : To assess the evidence and discuss the risks and clinical relevance of ketamine for the treatment of various disease states impacting the adult critically ill population. Data Sources : A literature review was performed using PubMed evaluating primary literature published until August 2018. Study Selection : Case reports, observational studies (cohort, case-control), and randomized controlled trials involving patients 18 years and older in a nonperioperative setting using either IV or intramuscular ketamine were included for analysis. Uses of [...]
Lire la suiteAppel urgent de la société civile : du cannabis médical pour nos aînés !, signataires, 20 avril 2020
Appel urgent de la société civile : du cannabis médical pour nos aînés ! Nous, associations d’usagers de cannabis à des fins thérapeutiques, médecins et travailleurs sociaux dans le champ des addictions, militants humanitaires appelons solennellement le ministre de la Santé, Olivier Véran, le gouvernement d’Edouard Philippe et le Président de la République, Emmanuel Macron, à rendre possible l’accès immédiat au cannabis à usage médical. Comme l’ont expliqué William Lowenstein et Jean-Yves Nau (Slate du 16 avril 2020), il est choquant que nos anciens reçoivent force benzodiazépines, antidépresseurs, neuroleptiques et opioïdes sans même que l’accès au cannabis à usage thérapeutique soit possible en [...]
Lire la suiteBibliographie Cannabinoïdes et CANCER Docteur Christian SUEUR, GRECC, avril 2020. 1 - Activité anti-tumorale des cannabinoïdes : 2 - 14 2 - Cannabinoïdes et Soins Palliatifs dans les pathologies cancéreuses : 15 - 17 3 - Cannabinoïdes et santé mentale en cancérologie : 18 4 - Cannabinoïdes et douleurs cancéreuses : 19 - 23 5 - Cannabinoïdes et chimiothérapies (nausées et vomissements) : 24 - 25
Lire la suiteImpact of co-administration of oxycodone and smoked cannabis on analgesia and abuse liability Ziva D. Cooper, Gillinder Bedi, Divya Ramesh, Rebecca Balter, Sandra D. Comer and Margaret Haney Neuropsychopharmacology, 2018, 0, 1–10 Doi : 10.1038/s41386-018-0011-2 Cannabinoids combined with opioids produce synergistic antinociceptive effects, decreasing the lowest effective antinociceptive opioid dose (i.e., opioid-sparing effects) in laboratory animals. Although pain patients report greater analgesia when cannabis is used with opioids, no placebo-controlled studies have assessed the direct effects of opioids combined with cannabis in humans or the impact of the combination on abuse liability. This double-blind, placebo-controlled, within-subject study determined if cannabis enhances the analgesic effects [...]
Lire la suiteDossier Cannabis thérapeutique Le regard de William Lowenstein par William Lowenstein SWAPS, 4e trimestre 2009, 57. KCacX13b est un cousin éloigné. Sa planète, que nous garderons anonyme pour des raisons évidentes de sécurité, est éloignée de 125 millions d’années lumières du ministère de l’Intérieur et de la Mildt. KCacX13b, que je surnomme CAC40 pour rire, adore nous rendre visite tous les dix ans, pour parler de la famille dit-il. Je pense qu’il vient surtout pour faire son marché. Du fait de la supérieure intelligence de son peuple et de sa non moins parfaite androïdité, l’incohérence et la stupidité ont disparu de sa planète depuis [...]
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