A Comparative Review of the Neuro- Psychopharmacology of Hallucinogen-Induced Altered States of Consciousness : The Uniqueness of Some Hallucinogens Ümit Sayin NeuroQuantology, June 2012, Volume 10, Issue 2, 316-340. eISSN 1303-5150 ABSTRACT Altered states of consciousness induced by hallucinogens (H-ASC) is still a vaguely understood phenomenon. Taken the diverse psychological effects they exert, the main mechanism of action of hallucinogens; LSD, ibogaine, THC, PCP, MDMA, methamphetamine, mescaline, psilocybin and DMT, of which psychological effects are discussed in the article, are not properly understood and explained by the modern methods of neuroscience due to the lack of vigorous research. The involvement of some receptors, such as, [...]
Lire la suiteThe Religious Significance of Entheogenic Drugs Hugh Asher More Info: This is my unpublished Master's Dissertation. Abstract This paper examines the use of psychoactive substances such as Psilocybin, Mescaline, and LSD as adjuncts to mystical, religious or spiritual experiences. There is an analysis of the psychological changes and the changes in perception that these substances cause and how these can be interpreted as contributing to religious or spiritual enlightenment. There is also a discussion on the nature of what could be considered a religious experience. An overview of the use of such ‘entheogenic’ drugs from an historical perspective follows, looking specifically at the use of [...]
Lire la suiteTherapeutic Applications of Ayahuasca and Other Sacred Medicines Michael J. Winkelman chapter 1, in B. Caiuby Labate and C. Cavnar (eds.) : "The Therapeutic Use of Ayahuasca", Springer-Verlag Berlin Heidelberg 2014 Doi : 10.1007/978-3-642-40426-9_1 Abstract : Therapeutic applications of the psychedelics or hallucinogens found cross-culturally involve treatment of a variety of physical, psychological, and social maladies. Modern medicine has similarly found that a range of conditions may be successfully treated with these agents. The ability to treat a wide variety of conditions derives from variation in active ingredients, doses and modes of application, and factors of set and setting manipulated in ritual. Similarities in effects reported [...]
Lire la suiteHenri Michaux et les gouffres (à propos de l’expérience mescalinienne) François Emmanuel « Moi n’est jamais que provisoire » (Plume). « J’écris pour me parcourir… » annonçait Henri Michaux. À l’hiver 1954 (il a cinquante-cinq ans) il a amplement parcouru le monde, descendu en pirogue un affluent de l’Amazone, promené son étrangeté en Inde, en Chine, en Malaisie…, ramené de ces pays lointains des notations buissonnières, éparses, décalées, des fables drolatiques. Çà et là il s’est fait entomologiste fantasque ou zoologiste d’animaux fantastiques. Toujours curieux de l’ailleurs mais toujours un peu déçu, il a délaissé ces contrées réelles pour d’autres imaginaires, s’est lancé [...]
Lire la suiteBibliographie : Substances psychédéliques et traitement des Addictions, Dr Christian Sueur, GRECC, novembre 2019 Ayahuasca, LSD, Kétamine, Psilocybine, Ibogaine, MDMA, Salvia divinorum et Mescaline, et traitement des Addictions
Lire la suitePsychiatry & the psychedelic drugs. Past, present & future James J.H. Rucker, Jonathan Iliff, David J. Nutt Neuropharmacology, 2018, 142, 200e218 https://doi.org/10.1016/j.neuropharm.2017.12.040 a b s t r a c t The classical psychedelic drugs, including psilocybin, lysergic acid diethylamide and mescaline, were used extensively in psychiatry before they were placed in Schedule I of the UN Convention on Drugs in 1967. Experimentation and clinical trials undertaken prior to legal sanction suggest that they are not helpful for those with established psychotic disorders and should be avoided in those liable to develop them. However, those with so-called ‘psychoneurotic’ disorders sometimes benefited considerably from their tendency to [...]
Lire la suiteTribune pour l’expérimentation des psychédéliques en médecine, contre la dépression, l’anxiété, les addictions et pour les soins palliatifs. Société Psychédélique Française, novembre 2019 D’après l’Organisation mondiale de la santé, une personne sur quatre dans le monde sera affectée à un moment donné de sa vie par des troubles mentaux ou neurologiques. Or, après des décennies d’oubli, nous assistons en dehors de nos frontières à un regain de la recherche clinique psychothérapeutique sur les psychédéliques et au développement de thérapies novatrices impliquant ces substances. Les psychédéliques sont des composés, issus du monde vivant ou de la chimie, provoquant des effets analogues sur le psychisme [...]
Lire la suiteHeaven and Hell Revisited Peter Webster Composed in 1996 for The Psychedelic Library How is it possible for two persons of such obvious intellectual talent as William Braden and Aldous Huxley to have such radically different experiences as a result of ingestion of a similar quantity of mescaline? Both Huxley and Braden brought to their first psychedelic experiment a wide knowledge and understanding of science, religion, mysticism, literature and fine arts, yet Huxley’s initial psychedelic experience was a revelation, and led to the writing of The Doors of Perception, a book which launched a movement, if not a revolution. William Braden’s experiment, recounted [...]
Lire la suiteMultiple receptors contribute to the behavioral effects of indoleamine hallucinogens Adam L. Halberstadt & Mark A. Geyer Neuropharmacology, 2011, 61, (3), 364–381. doi:10.1016/j.neuropharm.2011.01.017. Abstract Serotonergic hallucinogens produce profound changes in perception, mood, and cognition. These drugs include phenylalkylamines such as mescaline and 2,5-dimethoxy-4-methylamphetamine (DOM), and indoleamines such as (+)-lysergic acid diethylamide (LSD) and psilocybin. Despite their differences in chemical structure, the two classes of hallucinogens produce remarkably similar subjective effects in humans, and induce cross-tolerance. The phenylalkylamine hallucinogens are selective 5-HT2 receptor agonists, whereas the indoleamines are relatively nonselective for serotonin (5-HT) receptors. There is extensive evidence, from both animal and human studies, that the [...]
Lire la suitePsilocybin, Lysergic Acid Diethylamide, Mescaline, and Drug-Induced Synesthesia Berit Brogaard, Dimitria Electra Gatzia Neuropathology of Drug Addictions and Substance Misuse, 2016, Volume 2, chapter 83, 890-905. http://dx.doi.org/10.1016/B978-0-12-800212-4.00083-2 Copyright © 2016 Elsevier Inc. All rights reserved INTRODUCTION Synesthesia typically involves either the stimulation of one sensory modality giving rise to an experience in a different sensory modality (such as when a smell or taste gives rise to a color experience) or the stimulation of a single sensory modality giving rise to an unusual qualitative experience (such as when an achromatic grapheme appears colored) (Baron-Cohen, Wyke, & Binnie, 1987; Brogaard, 2012; Cytowic, 1989; Day, 2005; Rich & Mattingley, [...]
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