Catégorie : Substances psychédéliques et therapeutique

The LSD Therapy Career of Jan Bastiaans, M.D. Stephen Snelders, 1998

The LSD Therapy Career of Jan Bastiaans, M.D. Stephen Snelders Newsletter of the Multidisciplinary Association for Psychedelic Studies, MAPS : 1998, Vol 8, N° 1, pp. 18-20   JAN BASTIAANS WAS 23 YEARS OLD and a medical student at the University of Amsterdam when the German army invaded the Netherlands. The German occupation (1940-1945) had a lasting influence on his life and work. The first aim of Bastiaans' use of LSD and psilocybin in psychotherapy was to help victims of World War II: the survivors of the war who had become extremely traumatized by their experiences in the German and Japanese prisons and concentration [...]

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The Bastiaans Method of Drug-Assisted Therapy A preliminary follow-up study with former clients, Hans Ossebaard & Nicole Maalste, 1999

The Bastiaans Method of Drug-Assisted Therapy A preliminary follow-up study with former clients Hans Ossebaard & Nicole Maalste Bulletin of the Multidisciplinary Association for Psychedelic Studies, MAPS : 1999, Vol 9, N° 2, pp. 3-9 This study was made possible in part by a grant to MAPS from the Promind Foundation The present pilot study is a preliminary investigation among former clients who participated in therapy supervised by Bastiaans and his collaborators (see MAPS Bulletin, VIII (2), p. 3; 1998) and conducted with the help of hallucinogenic drugs. This follow-up study aims to systematically establish the subjective judgements of clients, to work out a profile that [...]

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Neurotoxicity and LSD treatment: a follow-up study of 151 patients in Denmark, Jens Knud Larsen, 2016

Neurotoxicity and LSD treatment : a follow-up study of 151 patients in Denmark Jens Knud Larsen University Hospital of Aarhus, Risskov, Denmark History of Psychiatry, 2016, Vol. 27, (2), 172–189 DOI: 10.1177/0957154X16629902   Abstract LSD was introduced in psychiatry in the 1950s. Between 1960 and 1973, nearly 400 patients were treated with LSD in Denmark. By 1964, one homicide, two suicides and four suicide attempts had been reported. In 1986 the Danish LSD Damages Law was passed after complaints by only one patient. According to the Law, all 154 applicants received financial compensation for LSD-inflicted harm. The Danish State Archives has preserved the case material of 151 [...]

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Les Champignons dans la culture. A propos d’un livre de M. R. G. Wasson, Claude Lévi-Strauss, 1970

Les Champignons dans la culture. A propos d'un livre de M. R. G. Wasson Claude Lévi-Strauss L'Homme, 1970, 10-1, pp. 5-16 On sait que les hymnes du RgVeda font une place considérable à une plante enivrante, le Soma, dont le suc exprimé et filtré, puis coupé de lait frais ou caillé, était consommé par les prêtres au cours du rituel et principalement, semble-t-il, par ceux chargés d'incarner le dieu Indra et son cocher Vâyu. Chez les anciens Iraniens, une boisson enivrante, appelée Haoma dans l'Avesta, était sans doute la même chose que le Soma. Depuis le xvme siècle, les [...]

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Le microdosage de substances psychédéliques : bref historique et nouveaux axes de recherche, Vittorio Biancardi,

Le microdosage de substances psychédéliques : bref historique et nouveaux axes de recherche Vittorio Biancardi Revue CIRCE, 2019, 11, 25pp   Résumé Le micro-dosage est un phénomène social de plus en plus répandu parmi la communauté des consommateurs et consommatrices des substances dites psychédéliques. Il consiste une consommation d’un dixième de la dose typique de substance (principalement LSD ou Psilocybine) de façon fréquente, deux ou trois fois par semaine, pour améliorer les capacités cognitives ou comme auto-thérapie. L’analyse de ce phénomène est actuellement très fragmentaire et inconsistante, tant du point de vue des sciences humaines que du point de vue des sciences dites «dures». L’objectif [...]

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The Association of Salvia divinorum and Psychotic Disorders: A Review of the Literature and Case Series, Joseph El-Khoury & Nayiri Sahakian, 2015

The Association of Salvia divinorum and Psychotic Disorders: A Review of the Literature and Case Series Joseph El-Khoury & Nayiri Sahakian Journal of Psychoactive Drugs, 2015, 47, 4, 286-292 https://doi.org/10.1080/02791072.2015.1073815   Abstract The association of substance abuse and psychotic disorders is of interest to clinicians, academics, and lawmakers. Commonly abused substances, such as cannabis, cocaine, amphetamines, and alcohol, have all been associated with substance-induced psychosis. Hallucinogens can induce desired psychedelic effects and undesirable psychomimetic reactions. These are usually transient and resolve once the duration of action is over. Sometimes, these effects persist, causing distress and requiring intervention. This article focuses on the hallucinogenic substance Salvia divinorum, [...]

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Chronic, Intermittent Microdoses of the Psychedelic N,N‑Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents, Lindsay P. Cameron et al., 2019

Chronic, Intermittent Microdoses of the Psychedelic N,N‑Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents Lindsay P. Cameron, Charlie J. Benson, Brian C. DeFelice, Oliver Fiehn, and David E. Olson ACS Chemical Neurosciences, 2019 DOI: 10.1021/acschemneuro.8b00692   ABSTRACT : Drugs capable of ameliorating symptoms of depression and anxiety while also improving cognitive function and sociability are highly desirable. Anecdotal reports have suggested that serotonergic psychedelics administered in low doses on a chronic, intermittent schedule, so-called “microdosing”, might produce beneficial effects on mood, anxiety, cognition, and social interaction. Here, we test this hypothesis by subjecting male and female Sprague Dawley rats to behavioral testing following the [...]

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Powerful substances in tiny amounts: Exploring the practice of microdosing psychedelic drugs, Petter Grahl Johnstad, 2017

Powerful substances in tiny amounts: Exploring the practice of microdosing psychedelic drugs Petter Grahl Johnstad Working Paper · December 2017 Nordic Studies on Alcohol and Drugs, 2018, Vol. 35(1) 39–51. Doi : 10.1177/1455072517753339   This article presents an explorative study of microdosing practices with psychedelic drugs. A microdose is defined as a sub-perceptual dose, commonly about one tenth of an ordinary recreational dose, which gives no alteration of consciousness or feeling of intoxication. Respondents (n = 17) were recruited at several Internet fora for individual interviews mediated via private messaging. Every participant was male, and the median respondent was in his 30s with a stable job [...]

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Motives and Side-Effects of Microdosing With Psychedelics Among Users, Nadia R. P. W. Hutten et al., 2019

Motives and Side-Effects of Microdosing With Psychedelics Among Users Nadia R. P. W. Hutten, Natasha L. Mason, Patrick C. Dolder, Kim P. C. Kuypers International Journal of Neuropsychopharmacology, 2019, 1–9 doi:10.1093/ijnp/pyz029   Abstract Background : Microdosing with psychedelics has gained considerable media attention where it is portrayed as a performance enhancer, especially popular on the work floor. While reports are in general positive, scientific evidence about potential negative effects is lacking aside from the prevalence and motives for use. The present study addressed this gap by surveying psychedelic users about their experience with microdosing including their dosing schedule, motivation, and potential experienced negative effects. Methods : An [...]

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The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act, Matthew W. Johnson et al., 2018

The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act Matthew W. Johnson, Roland R. Griffiths, Peter S. Hendricks, Jack E. Henningfiel Neuropharmacology, 2018, 142, 143-166. https://doi.org/10.1016/j.neuropharm.2018.05.012 a b s t r a c t This review assesses the abuse potential of medically-administered psilocybin, following the structure of the 8 factors of the US Controlled Substances Act (CSA). Research suggests the potential safety and efficacy of psilocybin in treating cancer-related psychiatric distress and substance use disorders, setting the occasion for this review. A more extensive assessment of abuse potential according to an 8-factor analysis would eventually be required to [...]

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