Catégorie : Substances psychédéliques et therapeutique

Salvia divinorum, EMCDDA, 2010

Salvia divinorum EMCDDA, 2010. http://www.emcdda.europa.eu/publications/drug-profiles/salvia/fr Chimie Forme physique Pharmacologie Origine Mode de consommation Autres dénominations Analyse Pureté typique Contrôle Prévalence Prix au détail Usage médical Bibliographie Lecture complémentaire Photo: Wikimedia Commons La plante psychotrope Salvia divinorum, ou «Sauge des devins», est un membre rare de la famille des menthes (Lamiaceae; anciennement Labiatae), qui a été caractérisée au milieu du vingtième siècle. La plante est endémique d’une petite région montagneuse de l’État d’Oaxaca (Mexique), où les Indiens mazatèques ingèrent ses feuilles fraîches ou des préparations à base de feuilles lors de rituels divinatoires, de rites de guérison ou à des fins médicales. Depuis la fin [...]

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You Have a Constitutional Right to Psychedelics. Academic Freedom, Personal Conscience, and Psychotechnologies, Thomas B. Roberts , 2016

  Chapter 1 : You Have a Constitutional Right to Psychedelics. Academic Freedom, Personal Conscience, and Psychotechnologies Thomas B. Roberts From: Ellens, H. J. & T. B. Roberts. 2015. The Psychedelic Policy Quagmire: Health, Law, Freedom, and Society. Santa Barbara, CA. ABC-CLIO. Author’s note: This also applies to the European Charter of Human Rights and to similar national and international statements. Added Mar. 16, 2016.   The problem : we do not suppress books and the ideas they contain; we do suppress psychedelic mindstates and the ideas they contain. Censorship is the issue of contention here: intellectual censorship. In this chapter, we’ll spot the single-state fallacy as [...]

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Psilocybin-Induced Deficits in Automatic and Controlled Inhibition are Attenuated by Ketanserin in Healthy Human Volunteers, Boris B. Quednow et al., 2012

Psilocybin-Induced Deficits in Automatic and Controlled Inhibition are Attenuated by Ketanserin in Healthy Human Volunteers Boris B Quednow, Michael Kometer, Mark A Geyer and Franz X Vollenweider Neuropsychopharmacology, 2012, 37, 630–640 doi:10.1038/npp.2011.228   The serotonin-2A receptor (5-HT2AR) has been implicated in the pathogenesis of schizophrenia and related inhibitory gating and behavioral inhibition deficits of schizophrenia patients. The hallucinogen psilocybin disrupts automatic forms of sensorimotor gating and response inhibition in humans, but it is unclear so far whether the 5-HT2AR or 5-HT1AR agonist properties of its bioactive metabolite psilocin account for these effects. Thus, we investigated whether psilocybin-induced deficits in automatic and controlled inhibition in healthy [...]

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Psilocybin, Lysergic Acid Diethylamide, Mescaline, and Drug-Induced Synesthesia, Berit Brogaard & Dimitria Electra Gatz, 2016

Psilocybin, Lysergic Acid Diethylamide, Mescaline, and Drug-Induced Synesthesia Berit Brogaard, Dimitria Electra Gatzia Neuropathology of Drug Addictions and Substance Misuse, 2016, Volume 2, chapter 83, 890-905. http://dx.doi.org/10.1016/B978-0-12-800212-4.00083-2 Copyright © 2016 Elsevier Inc. All rights reserved   INTRODUCTION Synesthesia typically involves either the stimulation of one sensory modality giving rise to an experience in a different sensory modality (such as when a smell or taste gives rise to a color experience) or the stimulation of a single sensory modality giving rise to an unusual qualitative experience (such as when an achromatic grapheme appears colored) (Baron-Cohen, Wyke, & Binnie, 1987; Brogaard, 2012; Cytowic, 1989; Day, 2005; Rich & Mattingley, [...]

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Psychedelic Elephant, Peter Webster, 2019

Psychedelic Elephant A critique of psychedelic research Peter Webster juillet 2019 https://www.researchgate.net/search.Search.html?type=researcher&query=Psychedelic%20Elephant   My title might lead some who are old enough to remember the incident 1 2 to expect from this essay an indictment of the idiots who conducted the "scientific research" during which an elephant was clearly murdered.3 It is always great fun to expose foolishness and willful ignorance. But unfortunately, psychedelic research in those days, the 1950s and 1960s, attracted no small number of other scientists who, at least in retrospect, could also be called idiots. Jean Houston (1967) has described one of her initial observations of LSD administration. The subject was told by [...]

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Integrating Psychedelic Medicines and Psychiatry : Theory and Methods of a Model Clinic, Jordan Sloshower, 2018

Integrating Psychedelic Medicines and Psychiatry : Theory and Methods of a Model Clinic Jordan Sloshower Chapter 7, In : Labate B., Cavnar C. (eds) : Plant Medicines, Healing and Psychedelic Science,  2018 © Springer International Publishing AG 2018 DOI: 10.1007/978-3-319-76720-8_7   Abstract The past two decades has seen a significant increase in both popular and scientific interest in psychedelic substances and plants as therapeutics for mental illness, addictions, and psychospiritual suffering. Current psychiatric practice privileges a biological paradigm in which the brain is considered the locus of mental illness and symptom-focused treatments are delivered to patients as passive recipients. In contrast, a psychedelic healing paradigm, constructed through [...]

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Expanding the Scientific Study of Self-Experience with Psychedelics, Manesh Girn and Kalina Christoff, 2018

Expanding the Scientific Study of Self-Experience with Psychedelics Manesh Girn and Kalina Christoff Journal of Consciousness Studies, 2018, 25, (11–12), 131–54 Abstract : The nature of the self has long been a topic of discussion in philosophical and religious contexts, and has recently also garnered significant scientific attention. Although evidence exists to suggest the multifaceted nature of self-experience, the amount of research done on each of its putative components has not been uniform. Whereas selfreflective processing has been studied extensively, non-reflective aspects of self-experience have been the subject of comparatively little empirical research. This discrepancy may be linked to the methodological difficulties in experimentally [...]

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The Influence of Psychedelic Induced Ego-Dissolution on Self-Compassion, Kevin Allan Stansbury, 2019

The Influence of Psychedelic Induced Ego-Dissolution on Self-Compassion Kevin Allan Stansbury B.A., 2011, California State University, Dominguez Hills, May 2019 A THESIS Presented to the School of Social Work California State University, Long Beach In Partial Fulfillment of the Requirements for the Degree Master of Social Work   Abstract Prior research has shown that psychedelic induced ego-dissolution mediates therapeutic outcomes and enhances well-being. The experience of psychedelics has been shown to increase certain mindfulness capacities. A cross-sectional descriptive study was implemented in an online community to examine the relationship between psychedelic induced ego-dissolution and self-compassion in adults who have used psychedelics in the past. This study also [...]

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Psychedelic drug use in healthy individuals : a review of benefits, costs, and implications for drug policy, James W.B. Elsey, 2017

Psychedelic drug use in healthy individuals : a review of benefits, costs, and implications for drug policy James W.B. Elsey Drug Science, Policy and Law, 2017, Vol 3, 1-11 DOI: 10.1177/2050324517723232   Abstract The potential of psychedelic drugs in the treatment of mental health problems is increasingly being recognized. However, relatively little thrust has been given to the suggestion that individuals without any mental health problems may benefit from using psychedelic drugs, and that they may have a right to do so. This review considers contemporary research into the use of psychedelic drugs in healthy individuals, including neurobiological and subjective effects. In line with findings [...]

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Psilocybin – Summary of knowledge and new perspectives, Filip Tylš et al., 2014

Psilocybin – Summary of knowledge and new perspectives Filip Tylš, Tomáš Páleníček, Jiří Horáček European Neuropsychopharmacology, 2014, 24, 342–356 Doi : 10.1016/j.euroneuro.2013.12.006   Abstract Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a research tool for modeling psychosis as well as due to its potential therapeutic effects. However, it is also a very popular and frequently abused natural hallucinogen. This review summarizes all the past and recent knowledge on psilocybin. It briefly deals with its history, discusses the pharmacokinetics and pharmacodynamics, and compares its action in humans and animals. It attempts to describe the mechanism of psychedelic effects [...]

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