Cannabis - from cultivar to chemovar A. Hazekamp and J. T. Fischedick Drug Testing and Analysis, 2012, (wileyonlinelibrary.com) DOI 10.1002/dta.407, Copyright © 2012 John Wiley & Sons, Ltd. Abstract : The medicinal use of Cannabis is increasing as countries worldwide are setting up official programs to provide patients with access to safe sources of medicinal-grade Cannabis. An important question that remains to be answered is which of the many varieties of Cannabis should be made available for medicinal use. Drug varieties of Cannabis are commonly distinguished through the use of popular names, with a major distinction being made between Indica and Sativa types. Although more than [...]
Lire la suiteThe Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis : no "Strain", no Gain Ethan B. Russo, Frontiers in Plant Science, 2019, Volume 9, Article 1969, 1-8. doi : 10.3389/fpls.2018.01969 The topic of Cannabis curries controversy in every sphere of influence, whether politics, pharmacology, applied therapeutics or even botanical taxonomy. Debate as to the speciation of Cannabis, or a lack thereof, has swirled for more than 250 years. Because all Cannabis types are eminently capable of cross-breeding to produce fertile progeny, it is unlikely that any clear winner will emerge between the “lumpers” vs. “splitters” in this taxonomical debate. This is [...]
Lire la suiteREVIEW-THEMED ISSUE Cannabis, from plant to pill Pr Christopher GROF, British Journal of Clinical Pharmacology, 2018, 84, 2463-2467 Correspondence Professor Christopher P. L. Grof, School of Environmental and Life Sciences, University of Newcastle, University Drive, Callaghan, NSW, 2308, Australia. Tel.: + 61 2 49215858; Fax: +61 2 4921 5361; 1 Centre for Plant Science, School of Environmental and Life Sciences, University of Newcastle, Newcastle, NSW 2308, Australia and 2 The Australian Centre for Cannabinoid Clinical and Research Excellence Hunter Medical Research Institute, Locked Bag 1000, New Lambton, NSW2305, Australia Keywords : cannabinoids, cannabis, flos, flower, terpenoids The therapeutic application of cannabis is attracting substantial public and clinical interest. [...]
Lire la suiteCannabis and the Anxiety of Fragmentation - A Systems Approach for Finding an Anxiolytic Cannabis Chemotype, B. S. Kamal, F. Kamal, D. E. Lantela, Frontiers in Neuroscience, 2018, 12, article 730. https://doi.org/10.3389/fnins.2018.00730 Abstract : Cannabis sativa is a medicinal herb with a diverse range of chemotypes that can exert both anxiolytic and anxiogenic effects on humans. Medical cannabis patients receiving organically grown cannabis from a single source were surveyed about the effectiveness of cannabis for treating anxiety. Patients rated cannabis as highly effective overall for treating anxiety with an average score of 8.03 on a Likert scale of 0 to 10 (0 = not effective, [...]
Lire la suiteJ Nat Prod. 2016 Feb 26;79(2):324-31. doi: 10.1021/acs.jnatprod.5b00949. Epub 2016 Feb 2. Evolution of the Cannabinoid and Terpene Content during the Growth of Cannabis sativa Plants from Different Chemotypes. Aizpurua-Olaizola O1,2, Soydaner U1, Öztürk E1, Schibano D1, Simsir Y1, Navarro P2, Etxebarria N2, Usobiaga A2. Author information 1 Aifame GmbH , Tüfi 450, 9105 Wald-Schönengrund, Switzerland. 2 Analytical Chemistry Department, University of the Basque Country (UPV/EHU) , Barrio Sarriena s/n, 48940 Leioa, Spain. Abstract The evolution of major cannabinoids and terpenes during the growth of Cannabis sativa plants was studied. In this work, seven different plants were selected: three each from chemotypes I and III [...]
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