Étiquette : hiv

Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis, Sara Arias et al., 2021

Clinical Evidence of Magistral Preparations Based on Medicinal Cannabis Sara Arias, Marta Leon, Diego Jaimes and Rosa-Helena Bustos Pharmaceuticals, 2021, 14, 78, 1-13. Doi :10.3390/ph14020078   Abstract : Cannabis has been widely used as a medicinal plant for millennia; however, studies related to its main components were first conducted in 1960. Subsequently, laboratories have produced new components and structures related to its active biological properties. Countries that have approved the medicinal use of cannabis impose regulations that govern its clinical and scientific use. One means of administering medicinal cannabis is via a magistral preparation that must have a medical prescription and be prepared in an establishment [...]

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Cannabinoids and the Coronavirus, Kevin P. Hill, 2020

Cannabinoids and the Coronavirus Kevin P. Hill Cannabis and Cannabinoid Research, 2020, Volume 5, Number 2, Doi : 10.1089/can.2020.0035   Introduction These are uncertain times as we attempt to manage our lives during the Coronavirus Covid-19 pandemic. It is not surprising, as possible treatments for Covid-19 are discussed, that people wonder about a role for cannabinoids, another topic associated with a lack of clarity about their therapeutic efficacy. Patients commonly ask clinicians about the benefits and risks of cannabinoids and now patients have begun to ask about cannabinoids as they relate to Covid-19. This interest creates an opportunity to strengthen the therapeutic alliance between patients and [...]

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Cannabis and Coronavirus : What Cannabis Patients Want to Know, Rxleaf.com, February 17, 2020

Cannabis and Coronavirus : What Cannabis Patients Want to Know Jennifer Grant https://www.rxleaf.com/cannabis-and-coronavirus-what-cannabis-patients-want-to-know/ February 17, 2020 There is evidence that cannabis can reduce viral load in HIV, can it help COVID-19 patients? At the time of writing, there were 69, 287 confirmed cases of the coronavirus and 1670 deaths. With the rapid escalation of the outbreak, these numbers will surely be outdated by the time of publication. With several regions heading into states of emergencies, including quarantine, nervous travelers are looking for anti viral herbs to reduce the chance of infection. Patients have asked us: What about cannabis? There have been rumors about successful treatments for coronavirus, [...]

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Cannabis Exposure is Associated With a Lower Likelihood of Neurocognitive Impairment in People Living With HIV, Caitlin Wei-Ming Watson et al., 2020

Cannabis Exposure is Associated With a Lower Likelihood of Neurocognitive Impairment in People Living With HIV Caitlin Wei-Ming Watson, Emily W. Paolillo, Erin E. Morgan, Anya Umlauf, Erin E. Sundermann, Ronald J. Ellis, MD, Scott Letendre, Thomas D. Marcotte, Robert K. Heaton, and Igor Grant Journal of Acquired Immune Deficiency Syndromes, 2020, 83, (1), 56–64. Doi : 10.1097/QAI.0000000000002211   Background : Aging and HIV have adverse effects on the central nervous system, including increased inflammation and neural injury and confer risk of neurocognitive impairment (NCI). Previous research suggests the nonacute neurocognitive effects of cannabis in the general population are adverse or null. However, in the [...]

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Beta-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain, Esraa Aly et al.,

Beta-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain Esraa Aly, Maitham A. Khajah and Willias Masocha Molecules, 2020, 25, 106; doi:10.3390/molecules25010106   Abstract : Neuropathic pain associated with nucleoside reverse transcriptase inhibitors (NRTIs), therapeutic agents for human immunodeficiency virus (HIV), responds poorly to available drugs. Smoked cannabis was reported to relieve HIV-associated neuropathic pain in clinical trials. Some constituents of cannabis (Cannabis sativa) activate cannabinoid type 1 (CB1) and cannabinoid type 2 (CB2) receptors. However, activation of the CB1 receptor is associated with side eects such as psychosis and physical dependence. Therefore, we investigated the effect of B-caryophyllene (BCP), [...]

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Priority Considerations for Medicinal Cannabis-Related Research, Marcel O. Bonn-Miller et al., 2019

Priority Considerations for Medicinal Cannabis-Related Research Marcel O. Bonn-Miller, Charles V. Pollack, Jr., David Casarett, Richard Dart, Mahmoud ElSohly, Larry Good, Manuel Guzman, Lumır Hanus, Kevin P. Hill, Marilyn A. Huestis, Eric Marsh, Susan Sisley, Nancy Skinner, Judith Spahr, Ryan Vandrey, Eugene Viscusi, Mark A. Ware, and Donald Abrams Cannabis and Cannabinoid Research, 2019, Volume 4, Number 3, 1-19. DOI: 10.1089/can.2019.0045   Keywords : medicinal cannabis; medical marijuana   Introduction and Rationale The National Academy of Sciences, Engineering, and Medicine’s 2017 publication The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research provided a significant contribution by synthesizing the existing evidence base [...]

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Can 3,4,-methylenedioxymethamphetamine therapy be used to treat alcohol use disorder ?, Ben SESSA, 2017

Can 3,4,-methylenedioxymethamphetamine therapy be used to treat alcohol use disorder ? Ben SESSA Journal of Psychedelic Studies, 2017,  1, (1), pp. 1–9 DOI: 10.1556/2054.01.2016.003   Treating people with alcohol use disorder has been an important target area for psychedelic research – both in the first studies of the 1950s and during the Psychedelic Renaissance of the last 10 years. To date, most studies have looked at the classical psychedelic drugs as adjuncts to psychotherapy; with attention paid to the psychospiritual aspect of the experience as a central therapeutic process in effecting abstinence from drinking. Psychotherapy assisted with 3,4,-methylenedioxymethamphetamine (MDMA) has never been explored for treating [...]

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Bibliographie : Cannabinoïdes et HIV/SIDA

Dr Christian Sueur, GRECC, août 2018. ABRAMS D.I., HILTON J.F., LEISER R.J. et al. : Short-term effects of cannabinoids in patients with HIV-1 infection : a randomized, placebo-controlled clinical trial, Annals of Internal Medicine, 2003, 139, 258-266. ABRAMS D.I., JAY C.A. et al : Cannabis in painful HIV-associated sensory neuropathy : a randomized placebo-controlled trial, Neurology, 2007, 68, 7, 515-521. ABRAMS D.I., COUEY P., SHADE S.B. et al. : Cannabinoid-Opioid Interaction in Chronic Pain, Clinical Pharmacology and Therapeutics, 2011, DOI : 10.1038/clpt.2011.188. AVRAHAM H.K. et al. : Impaired Neurogenesis by HIV-1-GP120 is rescued by genetic deletion of Fatty Acid Amide Hydrolase Enzyme, British Journal of Pharmacology, 2014. [...]

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Le Cannabis et les cannabinoïdes dans les pathologies HIV/SIDA

Dr Christian SUEUR, psychiatre, GRECC (Groupe de Recherches et d’Etudes Cliniques sur les Cannabinoïdes) Août 2018   Dès 1999, dans le rapport « Marijuana and Medicine : Assessing the Science Base », l’Académie de Médecine américaine affirmait le caractère thérapeutique du cannabis chez les patients atteints du SIDA : « The profile of cannabinoid drugs effects suggest that they are promising for treating wasting syndrome in AIDS patients. Nausea, appetite loss, pain and anxiety are all afflictions of wasting, and all can be mitigated by marijuana. Although some médications are more effective than marijuana for these problems, they are not equally effective in all patients. A rapid-onset (that [...]

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