Étiquette : Harmaline

Chemistry, pharmacology and medicinal properties of Peganum harmala L., Jinous Asgarpanah and Fereshteh Ramezanloo, 2012

Chemistry, pharmacology and medicinal properties of Peganum harmala L. Jinous Asgarpanah and Fereshteh Ramezanloo African journal of pharmacy and pharmacology, 2012, 6, (22), 1573-1580. Doi : 10.5897/AJPP11.876   Peganum harmala L. is known as Syrian rue, Wild rue and Harmal. P. harmala extracts are considered important for drug development, because they are reported to have numerous pharmacological activities in the Middle East, especially in Iran and Egypt. For a long time P. harmala has been used in traditional medicines for the relief of pain and as an antiseptic agent. P. harmala also have antibacterial, antifungal, antiviral, antioxidant, antidiabetic, antitumor, antileishmanial, insecticidal and cytotoxic activities and hepatoprotective and antinociceptive effects. Harmaline, [...]

Lire la suite

Distribution, Status, Pharmacological, and Traditional importance of Peganum harmala L., Nissar Ahmad Khan et al., 2017

Distribution, Status, Pharmacological, and Traditional importance of Peganum harmala L. Nissar Ahmad Khan, Aamir Raina, Nasir Aziz Wagay, Younas Rasheed Tantray International Journal of Advance research in Science and Engineering, 2017, 6, (8), 1887-1894. www.ijarse.com   ABSTRACT Peganum harmala L. Commonly known as Syrian rue, Wild rue or Harmal is native to arid and semi-arid regions of Northern African and Asian deserts that have spread to parts of the southwestern United States and Northern Mexico. It is a multipurpose medicinal plant with antimicrobial, antifungal, anti inflammatory, antidiabetic, anti cancerous, hypothermic and hallucinogenic activities. Phytochemical investigations has revealed the presences of a number of active alkaloids [...]

Lire la suite

Case report : A case of β-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract, Giampietro Frison et al., 2008

Case report : A case of β-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract Giampietro Frison, Donata Favretto, Flavio Zancanaro, Giorgio Fazzin, Santo Davide Ferrara Forensic Science International, 2008, 179, e37–e43 doi:10.1016/j.forsciint.2008.05.003   Abstract b-Carboline alkaloids harmine, harmaline, and tetrahydroharmine can stimulate the central nervous system by inhibiting the metabolism of amine neurotransmitters, or by direct interaction with specific receptors; they are found in numerous plants, including Peganum harmala, Passiflora incarnata and Banisteriopsis caapi, and in the entheogen preparation Ayahuasca, which is traditionally brewed using B. caapi to enhance the activity of amine hallucinogenic drugs. The ingestion of plant preparations containing b-carboline alkaloids may [...]

Lire la suite

Alkaloids Derived from Tryptophan : Harmine and Related Alkaloids, T. D. Nikam et al., 2013

Alkaloids Derived from Tryptophan : Harmine and Related Alkaloids T. D. Nikam, K. M. Nitnaware, and M. L. Ahire chapter 19, in K.G. Ramawat, J.M. Merillon (eds.), Natural Products, # Springer-Verlag, Berlin Heidelberg, 2013 Doi : 10.1007/978-3-642-22144-6_20   Contents 1 Synonyms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 554 2 [...]

Lire la suite

Switch to mania after ayahuasca consumption in a man with bipolar disorder : a case report, Alejandro G Szmulewicz et al., 2015

Switch to mania after ayahuasca consumption in a man with bipolar disorder : a case report Alejandro G Szmulewicz, Marina P Valerio and Jose M Smith International Journal of Bipolar Disorders, 2015, 3, (4), 1-3. DOI 10.1186/s40345-014-0020-y   Abstract Background : There is an increasing use of ayahuasca for recreational purposes. Furthermore, there is a growing evidence for the antidepressant properties of its components. However, there are no reports on the effects of this substance in the psychiatric setting. Harmaline, one of the main components of ayahuasca, is a selective and reversible MAO-A inhibitor and a serotonin reuptake inhibitor. Case report : We present the case of [...]

Lire la suite

A Psychotherapeutic View on the Therapeutic Effects of Ritual Ayahuasca Use in the Treatment of Addiction, Anja LOIZAGA-VELDER, 2013

A Psychotherapeutic View on the Therapeutic Effects of Ritual Ayahuasca Use in the Treatment of Addiction Anja LOIZAGA-VELDER MAPS Bulletin Special Edition, Spring 2013, 36-40.   Ayahuasca is a traditional plant preparation of the Amazon basin with psychoactive properties. In recent decades ayahuasca has gained the attention of researchers in multiple disciplines worldwide due to its acclaimed therapeutic and spiritual qualities. It is an admixture of two plants : the harmaline containing vine Banisteriopsis caapi, and the DMT-containing leafs from the Psychotria viridis bush. It is typically administered by a trained expert in a ritual context. The use of ayahuasca has spread beyond the Amazon [...]

Lire la suite

Ayahuasca-Assisted Therapy for Addiction : Results from a Preliminary Observational Study in Canada, Gerald Thomas et al., 2013

Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Gerald Thomas, Philippe Lucas, N. Rielle Capler, Kenneth W. Tupper and Gina Martin Current Drug Abuse Reviews, 2013, 6, (1), 1-13.   Abstract: Introduction : This paper reports results from a preliminary observational study of ayahuasca-assisted treatment for problematic substance use and stress delivered in a rural First Nations community in British Columbia, Canada. Methods : The “Working with Addiction and Stress” retreats combined four days of group counselling with two expert-led ayahuasca ceremonies. This study collected pre-treatment and six months follow-up data from 12 participants on several psychological and behavioral factors related to [...]

Lire la suite

Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution, M. V. Uthaug et al., 2018

Sub-acute and long-term effects of ayahuasca on affect and cognitive thinking style and their association with ego dissolution M. V. Uthaug, K. van Oorsouw, K. P. C. Kuypers, M. van Boxtel, N. J. Broers, N. L. Mason, S. W. Toennes, J. Riba, J. G. Ramaekers Psychopharmacology, 2018 https://doi.org/10.1007/s00213-018-4988-3   Abstract Rationale : Ayahuasca is a psychotropic plant tea from South America used for religious purposes by indigenous people of the Amazon. Increasing evidence indicates that ayahuasca may have therapeutic potential in the treatment of mental health disorders and can enhance mindfulness-related capacities. Most research so far has focused on acute and sub-acute effects of ayahuasca on [...]

Lire la suite

Ayahuasca and Public Health: Health Status, Psychosocial Well-Being, Lifestyle, and Coping Strategies in a Large Sample of Ritual Ayahuasca Users, Genís Ona et al., 2019

Ayahuasca and Public Health : Health Status, Psychosocial Well-Being, Lifestyle, and Coping Strategies in a Large Sample of Ritual Ayahuasca Users Genís Ona, Maja Kohek, Tomàs Massaguer, Alfred Gomariz, Daniel F. Jiménez, Rafael G. Dos Santos, Jaime E. C. Hallak, Miguel Ángel Alcázar- Córcoles & José Carlos Bouso Journal of Psychoactive Drugs, 2019, DOI: 10.1080/02791072.2019.1567961   ABSTRACT Assessing the health status of ayahuasca users has been challenging due to the limitations involved in randomized clinical trials and psychometric approaches. The main objective of this study is the implementation of an approach based on public health indicators. We developed a self-administered questionnaire that was administered to long-term [...]

Lire la suite