Étiquette : epilepsie

Species-specific susceptibility to cannabisinduced convulsions, Benjamin J Whalley et al., 2018

Species-specific susceptibility to cannabis-induced convulsions Benjamin J Whalley, Hong Lin, Lynne Bell, Thomas Hill, Amesha Patel, Roy A Gray, C Elizabeth Roberts, Orrin Devinsky, Michael Bazelot, Claire M Williams and Gary J Stephens British Journal of Pharmacology, 2018, 1-18. Doi : 10.1111/bph.14165   BACKGROUND AND PURPOSE Numerous claims are made for cannabis’ therapeutic utility upon human seizures, but concerns persist about risks. A potential confounder is the presence of both Δ9-tetrahydrocannabinol (THC), variously reported to be pro- and anticonvulsant, and cannabidiol (CBD), widely confirmed as anticonvulsant. Therefore, we investigated effects of prolonged exposure to different THC/CBD cannabis extracts on seizure activity and associated measures of endocannabinoid [...]

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Bibliographie : Cannabidiol (CBD), Docteur Christian SUEUR, GRECC, février 2020.

Bibliographie : Cannabidiol (CBD) Docteur Christian SUEUR, GRECC, février 2020.     voir aussi : Bibliographie : Cannabis et Cannabinoïdes en Psychiatrie, Bibliographie : Cannabinoïdes et neuroprotection Bibliographie : Cannabinoïdes et épilepsie Bibliographie : Interactions et antagonisme THC - CBD Bibliographie : Effets indésirables du Cannabis (thérapeutique) sur la Santé mentale Bibliographie : Cannabinoïdes, Dépression et Troubles de l’Humeur Bibliographie : Cannabinoïdes et PTSD Bibliographie : Cannabinoïdes et TSA/TED/psychoses infantiles Bibliographie : Cannabinoïdes et Maladies Neurodégénératives

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6 variétés de cannabis pleines de THCV, Aurélien BERNARD, Newsweed.fr, 30 janvier 2020

6 variétés de cannabis pleines de THCV Aurélien BERNARD Newsweed.fr, 30 janvier 2020 https://www.newsweed.fr/5-varietes-cannabis-thcv/ À mesure que les connaissances scientifiques sur le cannabis se développent, la composition chimique du cannabis et la manière dont il interagit avec le corps se dévoilent. Et si le CBD ou le THC sont largement étudiés, certains cannabinoïdes plus rares comme le THCV (tetrahydocannabivarine) intéressent de plus en plus les scientifiques. Au cours de la dernière décennie, des études sur des humains et des animaux ont identifié le potentiel du THCV pour réduire l’appétit chez les personnes qui luttent pour perdre du poids, réguler la glycémie chez les personnes atteintes [...]

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A Physician’s Guide to the Cannabidiol Craze, Angela Coombs & Diana M. Martinez, 2013

COMMENTARY A Physician's Guide to the Cannabidiol Craze Angela Coombs, MD; Diana M. Martinez, MD Medscape, May 31, 2019 Last month at the Columbia University Department of Psychiatry in upper Manhattan, Columbia chief psychiatry resident Dr Angela Coombs interviewed addiction expert Dr Diana Martinez on a number of issues related to the rising popularity and usage of cannabidiol (CBD). This transcript has been edited for clarity.   Angela Coombs, MD: Hi. My name is Dr Angela Coombs and I'm a chief resident here at Columbia. We are so happy to be able to have Dr Diana Martinez, who's a professor in psychiatry at Columbia and an expert [...]

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ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH, (Cannabis Indisa) Their Effects on the Animal System in Health, and their Utility in the Treatment of Tetanus and other Convulsive Diseases, W. B. O’SHAUGHNESSY, 1843

ON THE PREPARATIONS OF THE INDIAN HEMP, OR GUNJAH, (Cannabis Indisa) Their Effects on the Animal System in Health, and their Utility in the Treatment of Tetanus and other Convulsive Diseases. By W. B. O'SHAUGHNESSY, M.D., Bengal Army, Late Professor of Chemistry and Materia Medica in the Medical College of Calcutta. PROVINCIAL MEDICAL JOURNAL and Retrospect of the Medical Science No. 123. London, Saturday, February 4, 1843. [Concluded from p. 347.] experiments by the Author-Inferences as to the Acton of the Drug on Animals and Man.  

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Real-World Approaches to Cannabinoids in Pediatric-Onset Epilepsy: What Do the Data Tell Us? CME, Anup Patel, WWW.medscape.org, 2019

Real-World Approaches to Cannabinoids in Pediatric-Onset Epilepsy: What Do the Data Tell Us? CME Anup Patel, MD Posted: 12/19/2019 https://www.medscape.org/viewarticle/922715   Educational Impact Challenge The goal of this activity is to improve knowledge and competence related to the selection of cannabinoid-based therapies for pediatric-onset seizure disorders. Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers. What did you learn from this activity? Please click on the "Next" button to proceed to a brief survey to see how your [...]

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Medical cannabis trial will target 20,000 UK patients, Jamie Doward and Lily Gordon Brown, The Guardian, 3 novembre 2019.

Medical cannabis trial will target 20,000 UK patients Jamie Doward and Lily Gordon Brown The GUARDIAN, Published on Sun 3 Nov 2019 https://www.theguardian.com/society/2019/nov/03/medical-cannabis-uk-clinical-trial-patients-nhs   Project backed by Royal College of Psychiatrists aims to be largest on drug’s use in Europe • Medical cannabis: Why are doctors still not prescribing it? Tilray medicinal cannabis growing facility in Canada. Photograph: Tilray Up to 20,000 patients in the UK are to be given medical cannabis over a two-year period in an initiative that aims to create the largest body of evidence on the drug in Europe. The move, to be unveiled on Thursday, is [...]

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Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms : An Observational Study of 18 Participants Undergoing Compassionate Use, Paulo Fleury-Teixeira et al., 2019

Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms : An Observational Study of 18 Participants Undergoing Compassionate Use Paulo Fleury-Teixeira, Fabio Viegas Caixeta, Leandro Cruz Ramires da Silva, Joaquim Pereira Brasil-Neto and Renato Malcher-Lopes Frontiers in Neurology, October 2019, Volume 10, Article 1145 doi : 10.3389/fneur.2019.01145   Autism Spectrum Disorders comprise conditions that may affect cognitive development, motor skills, social interaction, communication, and behavior. This set of functional deficits often results in lack of independence for the diagnosed individuals, and severe distress for patients, families, and caregivers. There is a mounting body of evidence indicating the effectiveness of pure cannabidiol (CBD) and [...]

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CBD : The Cinderella Molecule, Martin A. LEE, projectCBD.org, 2017

CBD : The Cinderella Molecule Martin A. Lee On February 09, 2017 Originally published in High Times (Feb. 2017) https://www.projectcbd.org/culture/cbd-cinderella-molecule High Times cover story by Martin A Lee highlights the breakthrough research on CBD, and how it has revolutionized the story of cannabis medicine. “This changes everything!” That was the immediate reaction of Bay Area journalist Fred Gardner as he stood in the office of Steep Hill Laboratory in Oakland and eyed a chromatogram showing the unusual cannabinoid content of a hitherto unknown marijuana strain. The year was 2009, and the strain of interest, an oddity called Soma A-Plus, didn’t top the charts with THC (tetrahydrocannabinol), [...]

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