The effects of psilocybin on cognitive and emotional functions in healthy participants : Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation James J Rucker, Lindsey Marwood, Riikka-Liisa J Ajantaival, Catherine Bird, Hans Eriksson, John Harrison, Molly Lennard-Jones, Sunil Mistry, Francesco Saldarini, Susan Stansfield, Sara J Tai, Sam Williams, Neil Weston, Ekaterina Malievskaia and Allan H Young Abstract Background : Psilocybin, a psychoactive serotonin receptor partial agonist, has been reported to acutely reduce clinical symptoms of depressive disorders. Psilocybin’s effects on cognitive function have not been widely or systematically studied. Aim : The aim of this study was to [...]
Lire la suiteLSD enhances suggestibility in healthy volunteers R. L. Carhart-Harris, M. Kaelen, M. G. Whalley, M. Bolstridge, A. Feilding, D. J. Nutt Psychopharmacology, 2014 DOI 10.1007/s00213-014-3714-z Abstract Rationale : Lysergic acid diethylamide (LSD) has a history of use as a psychotherapeutic aid in the treatment of mood disorders and addiction, and it was also explored as an enhancer of mind control. Objectives : The present study sought to test the effect of LSD on suggestibility in a modern research study. Methods : Ten healthy volunteers were administered with intravenous (i.v.) LSD (40–80 μg) in a within-subject placebocontrolled design. Suggestibility and cued mental imagery were assessed using the Creative [...]
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