Étiquette : cadmium

Cannabidiol Protects Dopaminergic Neuronal Cells from Cadmium, Jacopo Junio Valerio Branca et al., 2019

Cannabidiol Protects Dopaminergic Neuronal Cells from Cadmium Jacopo Junio Valerio Branca, Gabriele Morucci, Matteo Becatti, Donatello Carrino, Carla Ghelardini, Massimo Gulisano, Lorenzo Di Cesare Mannelli  Alessandra Pacini International Journal of Environmental Research and Public Health, 2019, 16, 4420. doi : 10.3390/ijerph16224420   Abstract The protective effect of cannabidiol (CBD), the non-psychoactive component of Cannabis sativa, against neuronal toxicity induced by cadmium chloride (CdCl2 10 M) was investigated in a retinoic acid (RA)-dierentiated SH-SY5Y neuroblastoma cell line. CBD (1 M) was applied 24 h before and removed during cadmium (Cd) treatment. In dierentiated neuronal cells, CBD significantly reduced the Cd-dependent decrease of cell viability, and the rapid [...]

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