Hallucinogens and Their Therapeutic Use : A Literature Review Matthew J. BEGOLA, Jason E. SCHILLERSTROM Journal of Psychiatric Practice, 2019, 25, (5), 334–346 Doi : 10.1097/PRA.0000000000000409 The exploration of possible therapeutic benefitsof hallucinogenic substances has undergone a revitalization in the past decade. This literature review investigated the published literature regarding the psychotherapeutic uses of hallucinogens in psychiatric disorders. The results showed that a variety of substances have been evaluated in the treatment of psychiatric disorders, including ayahuasca, ibogaine, ketamine, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, and psilocybin. The conditions treated ranged from depression to autism, with the largest volume of research dedicated to substance use disorders. [...]
Lire la suiteThe Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity Robin L. Carhart-Harris, Kevin Murphy, Robert Leech, David Erritzoe, Matthew B. Wall, Bart Ferguson, Luke T.J. Williams, Leor Roseman, Stefan Brugger, Ineke De Meer, Mark Tanner, Robin Tyacke, Kim Wolff, Ajun Sethi, Michael A.P. Bloomfield, Tim M. Williams, Mark Bolstridge, Lorna Stewart, Celia Morgan, Rexford D. Newbould, Amanda Feilding, H. Val Curran, and David J. Nutt Biological Psychiatry, 2015, 78, 554-562. http://dx.doi.org/10.1016/j.biopsych.2013.12.015 ABSTRACT BACKGROUND : The compound 3,4-methylenedioxymethamphetamine (MDMA) is a potent monoamine releaser that produces an acute euphoria in most individuals. METHODS : [...]
Lire la suiteBibliographie "Salvia divinorum" Pharmacologie, Ethnopharmacologie, Neurophysiologie, Usages Thérapeutiques..., GRECC, Dr Christian Sueur, octobre 2019. Salvia divinorum : généralités, usages, sociologie.....................................................................................1 Salvia divinorum, Salvinorin A : Neurophysiologie..................................................................................4 Salvinorin A : Pharmacologie.....................................................................................................................7 Salvia divinorum et chamanisme..............................................................................................................11 Salvia divinorum et psychiatrie................................................................................................................12 Salvia divinorum et thérapeutique...........................................................................................................13
Lire la suiteThe Therapeutic Use of Ayahuasca Beatriz Caiuby LABATE, Clancy CAVNAR Editors, Springer-Verlag, Berlin, Heidelberg, 2014 Foreword Ancient Medicine and the Modern World Ayahuasca, the ‘‘great medicine’’ of the Amazon rain forest, was, for millennia, entirely unknown to Western Euro-American civilization. While first scientifically identified, catalogued, and recorded in the mid-nineteenth century by the English botanist and explorer Richard Spruce, it had earlier been the object of brutal suppression by Spanish and Portuguese invaders of the New World who attempted to violently extinguish its ceremonial use by the indigenous people of the Amazon. Employing the harshest measures of the Inquisition, in 1616, the Catholic Church [...]
Lire la suiteAssessment of the Psychotherapeutic Effects of Ritual Ayahuasca Use on Drug Dependency : A Pilot Study Xavier Fernández, Rafael Guimarães dos Santos, Marta Cutchet, Sabela Fondevila, Débora González, Miguel Ángel Alcázar, Jordi Riba, José Carlos Bouso, Josep María Fábregas, Xavier Fernández, Rafael Guimarães dos Santos in "The Therapeutic Use of Ayahuasca", Chapter 11, 183-196 Beatriz Caiuby LABATE, Clancy CAVNAR Editors, Springer-Verlag, Berlin, Heidelberg, 2014 First Online: 23 November 2013 Abstract Using personality, psychopathology, and neuropsychological assessment instruments, our team assessed the therapeutic effects of an ayahuasca ritual treatment. Data was collected at the Institute of Applied Amazonian Ethnopsychology (IDEAA), in the Brazilian Amazon Basin. Psychological assessments [...]
Lire la suiteEMA Panel Backs Esketamine Nasal Spray for Resistant Depression Megan Brooks Medscape Medical News, October 18, 2019 The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of esketamine nasal spray (Spravato, Janssen-Cilag) in combination with a selective serotonin reuptake inhibitor (SSRI) or serotonin and norepinephrine reuptake inhibitor (SNRI) for adults with treatment-resistant major depressive disorder (TRD). Patients are considered to have TRD if they have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode. Spravato will be available as a 28 mg nasal spray solution. The safety and [...]
Lire la suiteThe therapeutic potential of harmine and ayahuasca in depression : Evidence from exploratory animal and human studies Flávia de Lima Osório, Ligia Ribeiro Horta de Macedo, João Paulo Machado de Sousa, Joel Porfírio Pinto, João Quevedo, José Alexandre de Souza Crippa and Jaime Eduardo C. Hallak The Ethnopharmacology of Ayahuasca, chapitre 5, 2011, 75-85 Editor : Rafael Guimarães dos Santos ISBN: 978-81-7895-526-1 Abstract The high prevalence and the socio-functional impairment associated with depressive disorders, added to the limitations of currently available treatments, justify the search for novel pharmacological strategies for the management of depression. This chapter presents the major results of animal and human studies conducted [...]
Lire la suiteAyahuasca for Addiction ? That's a Trip Ayahuasca has long been used to heal the spirit, so what about addiction? Adi Jaffe, Psychology Today Posted Dec 10, 2018 https://www.psychologytoday.com/us/blog/all-about-addiction/201812/ayahuasca-addiction-thats-trip Doctors have been prescribing drugs to treat substance addictions for decades. Most commonly known is the use of buprenorphine and naloxone (Suboxone) in opioid addiction which provides some opioid activation, helping with withdrawal and cravings, without the same “high” and many of the associated psychosocial effects of illicit drug use. But Suboxone isn’t the only one – methadone, modafinil, naltrexone, ketamine, and many more examples exist in which the use of a chemical has been prescribed to help [...]
Lire la suiteCannabis thérapeutique : si tout va bien il ne sera pas disponible avant un certain temps Journalisme et Santé Publique Le blog de Jean-Yves Nau, journaliste et docteur en médecine 17 Octobre 2019 https://jeanyvesnau.com/2019/10/17/cannabis-therapeutique-si-tout-va-bien-il-ne-sera-pas-disponible-avant-un-certain-temps/ Bonjour Le temps de l’administration du médicament n’est pas celui du patient souffrant. Il y a un an on découvrait un mouvement de l’Agence nationale de sécurité médicament (ANSM) : « Évaluation de la pertinence et de la faisabilité de la mise à disposition du cannabis thérapeutique en France ». On apprenait alors qu’un Comité Scientifique Spécialisé Temporaire créé pour un an, aurait pour mission « d’évaluer la pertinence de développer en France l’utilisation thérapeutique du cannabis pour [...]
Lire la suiteAyahuasca in Adolescence : A Neuropsychological Assessment Evelyn Doering-Silveira, Enrique Lopez, Charles S. Grob, Marlene Dobkin de Rios, Luisa K. Alonso, Cristiane Tacla,Itiro Shirakawa, Paulo H. Bertolucci, & Dartiu X. Da Silveira Journal of Psychoactive Drugs, 2005, 37, (2), 123-128. Abstract The purpose of the study was to evaluate neuropsychologically adolescents who use ayahuasca in a religious context. A battery of neuropsychological tests was administered to adolescents who use ayahuasca. These subjects were compared to a matched control group of adolescents who did not use ayahuasca. The controls were matched with regards to sex, age, and education. The neuropsychological battery included tests of speeded [...]
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