Le Cannabidiol, l’autre canabinoïde présent dans le cannabis : une piste thérapeutique prometteuse? Traiter la dépendance avec du cannabidiol ? Si peu d’études ont pour l’heure été menées chez l’Homme, l’idée fait son chemin... et inspire les instigateurs d’une étude-pilote «CANNAVAP». Grégoire Cleirec et Pierre Poloméni Publié le 20 Mai 2019 par : Revue SWAPS n°90, "Du Cannabis Thérapeutique à la Régulation". http://vih.org/20190520/cannabidiol-lautre-canabinoide-present-cannabis-piste-therapeutique-prometteuse/141891 L’Agence nationale de sécurité du médicament (ANSM) a annoncé récemment la création d’un comité scientifique spécialisé sur «l’évaluation de la pertinence et de la faisabilité de la mise à disposition du cannabis thérapeutique en France». Une façon de combler notre retard. À [...]
Lire la suiteRevue SWAPS n°90: Du Cannabis Thérapeutique à la Régulation, 1er trimestre 2019 EDITO S’agissant de la disponibilité du cannabis thérapeutique en France, la ministre de la santé, Agnès Buzyn, avait quelque peu entrouvert la porte : «C’est peut-être un retard que la France a pris quant à la recherche et au développement du cannabis médical. D’autres pays l’ont fait. (…) il n’y a aucune raison d’exclure, sous prétexte que c’est du cannabis, une molécule qui peut être intéressante pour le traitement de certaines douleurs très invalidantes». De fait, l’Agence nationale de sécurité du médicament (ANSM) a annoncé récemment (lire page 21) la [...]
Lire la suiteA role for cannabidiol in psychiatry? Keep calm and follow the drug development rules Gabriella Gobbi THE WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2019, VOL. 20, NO. 2, 98–100 Commentary https://doi.org/10.1080/15622975.2019.1584680 Along with tetrahydrocannabinol (THC), cannabidiol (CBD) is one of the main pharmacological components of Cannabis sativa and indica. Unlike THC, which binds CB1 receptors, CBD does not cause any dependence, and acts mostly via 5-HT1A and TPRV1 receptors (De Gregorio et al. 2018). Khoury et al. (2019) recently published a systematic review on the role of cannabidiol in psychiatry in the World Journal of Biological Psychiatry. After analysing 609 articles, they found six case reports, [...]
Lire la suite3rd International Medical Cannabis Conference (CannX 2018) Tel Aviv, Israël, October 14–16, 2018 Medical Cannabis and Cannabinoids, 2018, 1, 119–129 Published online : October 4, 2018 DOI: 10.1159/000493905 Abstracts CANNX18-0023 Co-Culture, Stigma and Deprivations among Medical Cannabis Patients in Israel H. Bonny-Noach Ariel University, Department of Criminology, Ariel, Israel CANNX18-0039 Cannabis Is Personal: The Intersection Between Human Genetics and Cannabis L. May, CEO & Founder of EndoCanna Health, Seattle, USA CANNX18-0046 Rationale to Evaluate Community-Led Interventions Employing Cannabis as Harm Reduction During the Opioid Overdose Crisis M.J. Milloy1, K. Heed2 1British Columbia Centre on Substance Use, Research, Vancouver, Canada; 2GrowX Global, Operations, Vancouver- BC, Canada CANNX18-0041 Concrete Evidence of Medical Cannabis Saving Lives and How Data Can Help [...]
Lire la suiteCannabis – Phytochemical, Pharmacological and Clinical Evidence Scientific Symposium University of Vienna, Austria, November 15, 2018 Abstracts Organized by Herbal Medicinal Products Platform Austria (HMPPA) Society for Medicinal Plant and Natural Product Research (GA) Medical Cannabis and Cannabinoids, 2018, 1, 130–134 Published online: November 9, 2018 DOI: 10.1159/000494812 Breeding and Agronomical Techniques to Produce Medicinal Cannabis Gianpaolo Grassi CREA-CI, Research Centre for Cereal and Industrial Crops, Branch Station of Rovigo, Italy Cannabis Beyond the “Big Two” (THC and CBD)”: The Biological Potential of Minor Cannabinoids and of Non-Cannabinoid Constituents of Cannabis Giovanni Appendino1, Eduardo Muñoz2 1Dipartimento di Scienze del Farmaco, Largo Donegani 2, 28100 Novara, Italy; 2Maimonides Biomedical Research Institute of Córdoba. Avda Menendez Pidal s/n, 14004 Cordoba, [...]
Lire la suiteExtractions of Medical Cannabis Cultivars and the Role of Decarboxylation in Optimal Receptor Responses Melissa M. Lewis-Bakker, Yi Yang, Rupali Vyawahare, and Lakshmi P. Kotra Cannabis and Cannabinoid Research, 2019, Volume X, Number X, 2019 Mary Ann Liebert, Inc. DOI: 10.1089/can.2018.0067 Abstract Introduction : Phytocannabinoids, characteristic compounds produced by medical cannabis, interact with cannabinoid (CB) receptors (CB1 and CB2) as well as other receptor systems to exhibit their corresponding pharmacological effects. In their natural form, CBs such as D9-tetrahydrocannabinolic acid and cannabidiolic acid are inactive at these receptors, while their decarboxylated forms (D9 tetrahydrocannabinol and cannabidiol, respectively) are potent ligands at CB receptors. Thus, extraction and [...]
Lire la suiteCannabis found to be cost-effective adjunctive therapy for neuropathy Second-line inhaled cannabis was found to be cost-effective in treating chronic neuropathic pain, according to a study in Cannabis and Cannabinoid Research. Griffin A. Tyree at the University of California San Diego is the lead author of a paper describing a model to simulate the cost and quality-adjusted life years of usual care with and without smoked cannabis as an adjunctive therapy with first-, second- and third-line treatments. Adding cannabis to second-line therapies was found to be more cost-effective than adding it to first- or third-line therapies. May 14, 2019 Learn More People on the [...]
Lire la suiteFor Registration click here For Scientific Program click here Program Highlights Translational Research Program Surrounding Cannabis and Cannabinoids Carolyn Baglole, McGill University, Canada The Endocannabinoid System as a Novel Therapeutic Target for Pain and CNS Disorders: Can the Promise be Realised? David Finn, National University of Ireland, Ireland Psychosocial Consequences of Regular Recreational Cannabis Use Eva Hoch, Ludwig Maximilian University, Germany Position of the European Pain Federation EFIC® on Appropriate Use of Cannabis‐Based Medicines and Medical Cannabis for Chronic Pain Management Bart Morlion, European Pain Federation EFIC, Belgium State of Medical Cannabis Education in the EU and the World Gregor Zorn, European Cannabinoid Therapy Association - ECTA, Slovenia Long-Term Treatment with Cannabis in Fibromyalgia Piercarlo Sarzi-Puttini, ASST Fatebenefratelli-Sacco, University of Milan, Italy Systematic Review [...]
Lire la suiteA Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy Ben Sessa, Laurie Higbed and David Nutt Frontiers in Psychiatry, 2019, Vol. 10, article 138 DOI : 10.3389/fpsyt.2019.00138 Neuropsychopharmacology Unit, Department of Medicine, Imperial College London, London, United Kingdom Abstract : This paper provides a brief review of the history, proposed pharmacological mechanisms, safety issues, and clinical applications of the medicine 3,4-methylenedioxymethamphetamine (MDMA). Most clinical MDMA research in patients to date has focused on MDMA-assisted psychotherapy to treat posttraumatic stress disorder (PTSD). In this review paper other potential therapeutic applications for MDMA therapy are described, including contemporary studies treating anxiety associated with autism and the authors’ ongoing study exploring the potential [...]
Lire la suitePRÉ-PROGRAMME : USAGES CLINIQUES des CANNABINOÏDES 24es PROFESSIONNELLES RENCONTRES DU RESPADD RÉSEAU DES ÉTABLISSEMENTS DE SANTÉ POUR LA PRÉVENTION DES ADDICTIONS En collaboration avec le GRECC (Groupe de Recherche et d’Etudes Cliniques sur les Cannabinoïdes) 20 et 21 JUIN 2019 PARIS ESPACE DU CENTENAIRE Quai de la Rapée 75012 Paris 9h30 – Accueil 10h00-12h30> Session Groupe de Recherche et d’Etudes Cliniques sur les Cannabinoïdes Président de séance : Christian Sueur, président du GRECC 10h00 – 10h30> Ouverture Ville de Paris, (sous réserve) ARS Ile-de-France, (sous réserve) Christian Sueur, président du GRECC 10h30 – 12h30 ÉTAT DES LIEUX DES ESSAIS CLINIQUES SUR LES CANNABINOÏDES EN FRANCE Discutant : Rodolphe Ingold, GRECC > Utilisation du Marinol en France : enquête [...]
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