Cannabinoids Identification in Lung Tissues of Young Cannabis Smokers Operated for Primary Spontaneous Pneumothorax and Correlation with Pathologic Findings Mario Bisconti, Giuseppe Marulli, Roberta Pacifici, Francesco Sollitto, Giulia Nex, Xenia Trabucco, Nicoletta Pia Ardò, Maria Concetta Rotolo, Giulia De Iaco, Teodora Panza, Debora Brascia, Marcella Schiavone, Francesca Signore, Francesco Pistelli, Angela De Palma Respiration, 2019. Doi : 10.1159/000503456 Abstract Background : Several studies suggested the association between tobacco and cannabis smoking and the risk of primary spontaneous pneumothorax (PSP), but none demonstrated cannabinoids in human lung tissues. Objectives : The aim of this study was to identify cannabinoids in lung specimens of young cannabis smokers, operated [...]
Lire la suiteThe association between regular cannabis use, with and without tobacco co-use, and adverse cardiovascular outcomes : cannabis may have a greater impact in non-tobacco smokers Theresa Winhusen, Jeff Theobald, David C. Kaelber, and Daniel Lewis The American Journal of Drug and Alcohol Abuse, 2019 https://doi.org/10.1080/00952990.2019.1676433 ABSTRACT Background : Understanding the potential impact of cannabis use on cardiovascular health is increasingly important as cannabis use rises in the U.S. Objectives : This study evaluated the associations between regular cannabis use, with and without tobacco co-use, and cardiovascular outcomes. Methods : Analysis of a limited dataset obtained through IBM Watson Health Explorys, a platform integrating electronic health record data. [...]
Lire la suitePatient-reported use of medical cannabis for pain, anxiety, and depression symptoms : Systematic review and meta-analysis Jesse D. Kosiba, Stephen A. Maisto, Joseph W. Ditre Social Science & Medicine, 2019, 181-192. https://doi.org/10.1016/j.socscimed.2019.06.005 This study is the first to conduct a systematic review and meta-analysis of empirical studies that assess patient-reported reasons for using medical cannabis to alleviate pain, anxiety, and depression. The present review further assessed the quality of studies and identified several methodological flaws in extant research. Highlights •Systematically reviewed studies why patients use medical cannabis. •Pain was a common reason for medical cannabis use (64%). •Anxiety (50%) and depression (34%) were [...]
Lire la suiteThe Role of Cannabis in Treating Anxiety : An Update Michael Van Ameringen; Jasmine Zhang; Beth Patterson; Jasmine Turna Current Opinion in Psychiatry, 2019, 33, (1), 1-7. DOI : 10.1097/YCO.0000000000000566 https://www.medscape.com/viewarticle/922111?nlid=133169_425&src=WNL_mdplsfeat_191224_mscpedit_psyc&uac=292598PZ&spon=12&impID=2219742&faf=1 Abstract and Introduction Abstract Purpose of review: Cannabis use for medical purposes has become increasingly common, including as treatment for mental health disorders such as anxiety. Unfortunately, the evidence examining its use in mental health has been slow to evolve, but is emerging. Given the widespread use of cannabis, it is important for both clinicians and those who suffer with anxiety to understand the effects of cannabis on symptoms of anxiety. In this review, we present [...]
Lire la suiteSoigner l'alcoolisme et la dépression avec des psychédéliques? Entretien avec David Nutt #RTSsanté , 11 avril 2019 https://www.youtube.com/watch?time_continue=55&v=D8QNY2bdNCk&feature=emb_logo Vidéo en complément du reportage « Le retour des psychédéliques » : https://youtu.be/503cSLA0Z38 Parmi les très nombreux articles cosignés par le Professeur David J. NUTT, du Psychedelic Research Group, Department of Medicine, Imperial College London, London, United Kingdom, les références suivantes sont disponibles sur le site du GRECC : Dissociable effects of cannabis with and without cannabidiol on the human brain’s resting-state functional connectivity, Matthew B. Wall, Rebecca Pope, Tom P. Freeman, Oliwia S. Kowalczyk, Lysia Demetriou, Claire Mokrysz, Chandni Hindocha, Will Lawn, Michael A.P. Bloomfield, Abigail M. [...]
Lire la suiteReal-World Approaches to Cannabinoids in Pediatric-Onset Epilepsy: What Do the Data Tell Us? CME Anup Patel, MD Posted: 12/19/2019 https://www.medscape.org/viewarticle/922715 Educational Impact Challenge The goal of this activity is to improve knowledge and competence related to the selection of cannabinoid-based therapies for pediatric-onset seizure disorders. Before you begin this activity, please assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers. What did you learn from this activity? Please click on the "Next" button to proceed to a brief survey to see how your [...]
Lire la suiteBibliographie : Thérapeutiques psychédélique Dr Christian Sueur, GRECC, décembre 2019 Voir également : Bibliographie : LSD Bibliographie : Ayahuasca Bibliographie : Psilocybine Bibliographie : Kétamine Bibliographie : Salvia divinorum Bibliographie : Mescaline
Lire la suiteBIBLIOGRAPHIE : Psilocybes, psilocybine. Dr Christian SUEUR, GRECC, décembre 2019 Psilocybes, psilocybine : généralités ..............................1 Psilocybes : ethnologie ...................................................2 Psilocybine : clinique psychiatrique ..............................4 Psilocybine : pharmacologie ..........................................5 Psilocybine : toxicologie - "effets indésirables" .............7 Psilocybine : neurophysiologie ......................................9 Psilocybine : expériences mystiques .............................13 Psilocybine : thérapie psychédélique ............................15-19
Lire la suiteBIBLIOGRAPHIE : Substances psychédéliques : Pharmacologie, Neurophysiologie, Psychologie, Dr Christian SUEUR, GRECC, décembre 2019 Cf également : Bibliographie : Thérapies psychédéliques, Bibliographie : Substances psychédéliques, Culture, Spiritualité, Chamanisme Bibliographie : Psilocybine, Bibliographie : LSD, Bibliographie : Ayahuasca….
Lire la suiteThe psychedelic renaissance : the next trip for psychiatry ? J. R. Kelly, A. Baker, M. Babiker, L. Burke, C. Brennan and V. O’Keane Irish Journal of Psychological Medicine, 2019, 1 - 5 doi : 10.1017/ipm.2019.39 Abstract The psychedelic research renaissance is gaining traction. Preliminary clinical studies of the hallucinogenic fungi, psilocybin, with psychological support, have indicated improvements in mood, anxiety and quality of life. A seminal, open-label study demonstrated marked reductions in depression symptoms in participants with treatment-resistant depression (TRD). The associated neurobiological processes involve alterations in brain connectivity, together with altered amygdala and default mode network activity. At the cellular level, psychedelics promote [...]
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