Demystifying Cannabis Daniele Piomelli, Cannabis and Cannabinoid Research, Volume 4, Number 1, 2019 Mary Ann Liebert, Inc. DOI: 10.1089/can.2019.29012.edi Every new book by Malcolm Gladwell goes, by default, straight to the top of my reading list. In the unlikely event that you are not familiar with the work of this Canadian author, make time to read The Tipping Point (Little, Brown and Co., 2000) or Outliers (Little, Brown and Co., 2008), and you will see why. Not only Gladwell is remarkably well informed and clear, as one would expect from an accomplished writer and public speaker, but he also has an unusual knack for uncovering [...]
Lire la suiteIncreased nature relatedness and decreased authoritarian political views after psilocybin for treatment-resistant depression LYONS T., CARHART-HARRIS R.L. Journal of Psychopharmacology, 2018, 32, 7, 811-819. Doi : 10.1177/0269881117748902 journals.sagepub.com/home/jop Abstract Rationale : Previous research suggests that classical psychedelic compounds can induce lasting changes in personality traits, attitudes and beliefs in both healthy subjects and patient populations. Aim : Here we sought to investigate the effects of psilocybin on nature relatedness and libertarian authoritarian political perspective in patients with treatment-resistant depression (TRD). Methods : This open-label pilot study with a mixed-model design studied the effects of psilocybin on measures of nature relatedness and libertarian– authoritarian political perspective in patients with [...]
Lire la suiteEffects of psilocybin therapy on personnality structure ERRITZOE D., ROSEMAN L., NOUR M.M., MacLEAN K., KAELEN M., NUTT D.J., CARHART-HARRIS R.L. Acta Psychiatrica Scandinavica, 2018, 1-11. DOI : 10.1111/acps.12904 . Objective : To explore whether psilocybin with psychological support modulates personality parameters in patients suffering from treatment-resistant depression (TRD). Method : Twenty patients with moderate or severe, unipolar, TRD received oral psilocybin (10 and 25 mg, one week apart) in a supportive setting. Personality was assessed at baseline and at 3-month follow-up using the Revised NEO Personality Inventory (NEO-PI-R), the subjective psilocybin experience with Altered State of Consciousness (ASC) scale, and depressive symptoms with QIDS-SR16. Results : [...]
Lire la suiteQuality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Leor Roseman, David J. Nutt, Robin L. Carhart-Harris Psychedelic Research Group, Department of Medicine, Imperial College London, London, United Kingdom Frontiers in Pharmacology, 2018, 8, article 974. Doi : 10.3389/fphar.2017.00974 . Introduction : It is a basic principle of the “psychedelic” treatment model that the quality of the acute experience mediates long-term improvements in mental health. In the present paper we sought to test this using data from a clinical trial assessing psilocybin for treatment-resistant depression (TRD). In line with previous reports, we hypothesized that the occurrence and magnitude of Oceanic Boundlessness (OBN) [...]
Lire la suiteCannabis and anxiety: a critical review of the evidence José Alexandre Crippa, Antonio Waldo Zuardi, Rocio Martin-Santos, Sagnik Bhattacharyya, Zerrin Atakan, Philip McGuire and Paolo Fusar-Poli Human Psychopharmacology Clinical and Experimental, 2009, 24, 515-523. Background : Anxiety reactions and panic attacks are the acute symptoms most frequently associated with cannabis use. Understanding the relationship between cannabis and anxiety may clarify the mechanism of action of cannabis and the pathophysiology of anxiety. Aims of the present study were to review the nature of the relationship between cannabis use and anxiety, as well as the possible clinical, diagnostic and causal implications. Method : Systematic review of the [...]
Lire la suitePsychedelics and hypnosis : Commonalities and therapeutic implications Clément E. Lemercier, Devin B. Terhune Journal of Psychopharmacology, 2018, 32, 7, 732-740. DOI : 10.1177/0269881118780714 Abstract Background : Recent research on psychedelics and hypnosis demonstrates the value of both methods in the treatment of a range of psychopathologies with overlapping applications and neurophenomenological features. The potential of harnessing the power of suggestion to influence the phenomenological response to psychedelics toward more therapeutic action has remained unexplored in recent research and thereby warrants empirical attention. Aims : Here we aim to elucidate the phenomenological and neurophysiological similarities and dissimilarities between psychedelic states and hypnosis in order to revisit [...]
Lire la suiteReducing the risks of drug use: The case for set and setting PHIL DALGARNO & DAVID SHEWAN Addiction Research and Theory, 2005, 13, 3, 259–265 Abstract : The central proposition of this article is that if people are thoughtful, well-prepared and aware of the means and best environments for using a particular drug, then the risks associated with the use of a particular drug – any drug – can be minimal. The types of drugs discussed in this context focus on those assumed to be the most ‘addictive’ – heroin and cocaine – to those less well-known but potentially more hazardous to use without [...]
Lire la suiteModel of Passion Applied to Recreational Marijuana Consumption Alan K Davis, Addiction Research & Theory, 2017, 25, 3, 188-194 Published online 2016 Dec 5. doi: 10.1080/16066359.2016.1242722 Abstract : This study was designed to evaluate the application of the dualistic model of passion (Vallerand, 2015; Vallerand et al., 2003) to recreational marijuana consumption. Using a web-based recruitment and data collection procedure, an online sample of 524 frequent marijuana consumers were administered a modified version of the Passion Scale (Marijuana-Harmonious and Obsessive Passion Scale; M-HOPS) and other questionnaires. Results from a canonical correlation analysis indicated that obsessive passion scores were significantly positively associated with past 30-day consumption, [...]
Lire la suiteCultural Neurophenomenology of Psychedelic Thought: Guiding the “Unconstrained” Mind Through Ritual Context Michael LIFSHITZ, Eli SHEINER, and Laurence J. KIRMAYER The Oxford Handbook of Spontaneous Thought : Mind-Wandering, Creativity, and Dreaming Edited by Kalina Christoff and Kieran C.R. Fox, avril 2018 Abstract : This chapter explores psychedelics as catalysts of spontaneous thought. Classic serotonergic psychedelics such as psilocybin, LSD, and ayahuasca can induce potent alterations in cognition and perception. The chapter reviews research on these substances through the lens of cultural neurophenomenology, which aims to trace how neurobiology and sociocultural factors interact to shape experience. After a decades-long hiatus, the scientific study of psychedelics is rediscovering [...]
Lire la suite« Heureusement qu’il y a l’herbe ! » Anne Coppel, Chimères, 2014, 82. « On ne trouve pas trace dans les livres, ni ailleurs, du nom de Govan-Eremetus, ni du pays d’Archaos où il régna, entre la fin des Temps-Barbares et le commencement des Temps-Barbares Pourtant quelque chose manque là, à la fois dans le temps et dans l’espace. A ce tournant mal éclairé de l’histoire, il y a comme un trou, des évènements postérieurs restent inexpliqués. Les coordonnées ne se rejoignent pas ; à partir d’un certain point on les perd (…) Nous avons longuement spéculé au bord de notre trou. C’est au petit matin, dans les fumées [...]
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